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Product Name | TIGIT, 22-141aa, Human, hIgG-His-tag, Baculovirus |
Description | Purity: > 90% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.. TIGIT, also known as T-cell immunoreceptor with Ig and ITIM domains, is a surface protein containing and immunoglobulin variable domain. This protein is expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells. Also, it binds with high affinity to the poliovirus receptor which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. Recombinant human TIGIT, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
Size | 250ug, 50ug, 10ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | T-cell immunoreceptor with Ig and ITIM domains, TIGIT, VSIG9, VSTM3, WUCAM |
Gene, Accession, CAS # | NP 776160 |
Catalog # | ATGP3704 |
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Order / More Info | TIGIT, 22-141aa, Human, hIgG-His-tag, Baculovirus from ATGen |
Product Specific References | n/a |
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