| 产品详情 |
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| Product Name | CAY10681 |
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| Description | A dual modulator of p53-MDM2 interaction and NF-κB signaling; binds MDM2 (Ki = 250 nM), reducing MDM2-mediated turnover of p53; inhibits phosphorylation of IκBα and dose-dependently reduces nuclear accumulation of p65; inhibits cancer cell growth in vitro and in vivo |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | biochemical inhibitor cancer intracellular signaling gene regulation inflammation NF-κB dual modulator p53-MDM2 interaction bind mediated turnover inhibit phosphorylation IκBα reduce reduction nuclear accumulation p65 block proliferation cell line oral bioavailability bioavailable tumor growth A549 xenograft in vivo vitro |
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| Gene, Accession, CAS # | CAS: 1542066-69-2 |
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| Catalog # | 15573-1 |
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| Price | |
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| Order / More Info | CAY10681 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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