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| Product Name | CAY10682 |
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| Description | Inhibits the p53-Mdm2 interaction (Ki = 83 nM) and also dose-dependently reduces activation of the NF-κB pathway; prevents phosphorylation of IκBα by IKKα, IKKβ, and IKK? (IC50s = 80.5, 78.2, and 57.1 µM, respectively); inhibits the growth of A549 cell xenografts in mice |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | biochemicals cancer intracellular signaling dual interaction inhibitors inhibit gene regulation NF-κB NFκB pathyway p53-Mdm2 p53Mdm2 interaction pyrrolo[3,4c]pyrazole derivative (+)-nutlin-3 phosphorylation of IκBα kinase IKKα IKKβ IKK? A549 cell xenograft CAY 10682 |
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| Gene, Accession, CAS # | CAS: 1542066-74-9 |
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| Catalog # | 15574-10 |
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| Order / More Info | CAY10682 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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