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Product Name | Plasminogen Activator Inhibitor Type 1, stable mutant, Human (PAI-1) |
Description | Plasminogen Activator Inhibitor 1 (PAI-1) is a glycoprotein found in plasma that is implicated in the processes of angiogenesis, hemostasis, tumor metastasis, fibrionlysis, ovulation, embryonic development and inflammation (1). The elevation of PAI-1 has shown to correlate with the prognosis of many cancers including breast cancer (2,3,4). PAI-1 is activated by the glycoprotein vitronectin. Vitronectin binds to PAI-1 and modulates fibrinolysis and cell migration (5). This binding has proven to be an important inhibitor of the activated form of protein C (APC) (6). Physical |
Size | 500ug |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | P4256-29S |
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Order / More Info | Plasminogen Activator Inhibitor Type 1, stable mutant, Human (PAI-1) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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