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Product Name | Plasminogen Activator Inhibitor Type 1, Wild Type Latent, Rat (HEPES Buffer) (PAI-1) |
Description | Purity ≥95% (SDS-PAGE). Plasminogen Activator Inhibitor 1 (PAI-1) is a glycoprotein found in plasma that is implicated in the processes of angiogenesis, hemostasis, tumor metastasis, fibrionlysis, ovulation, embryonic development and inflammation. The elevation of PAI-1 has shown to correlate with the prognosis of many cancers including breast cancer. PAI-1 is activated by the glycoprotein vitronectin. Vitronectin binds to PAI-1 and modulates fibrinolysis and cell migration. This binding has proven to be an important inhibitor of the activated form of protein C (APC). Concentration of Active PAI-1: Not detectable by SDS-PAGE Solubility: >2mg/ml and <5mg/ml |
Size | 500ug |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | P4256-29X |
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Order / More Info | Plasminogen Activator Inhibitor Type 1, Wild Type Latent, Rat (HEPES Buffer) (PAI-1) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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