产品详情 |
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Antigenic Specificity | LPAM-1 (Integrin a4b7) |
Clone | DATK32 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | purified |
Size | 500 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC), IHC, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-mouse LPAM-1 (Integrin α4β7). DATK32 antibody is specific for a combinatorial determinate of integrin α4β7complex. Integrin α4β7 is composed of a 150 kD (α4 or CD49d) and a 130 kD (β7) heterodimer, also known as CD49d/β7 or LPAM-1. Belonging to the Ig superfamily, it is found on the majority of peripheral lymphocytes and subsets of thymocytes and bone marrow cells (including mast cell progenitors). Integrin α4β7 binds its ligands, VCAM-1 (CD106), MAdCAM-1 and fibronectin, and plays an important role in lymphocytes adhesion and the direction of migration of blood lymphocytes to the intestine and associated lymphoid tissues. |
Immunogen | TK1 cells |
Other Names | α4β7 Integrin, CD49d/β7, LPAM-1 |
Gene, Accession # | Gene ID: 311144, 25713 |
Catalog # | 120602 |
Price | |
Order / More Info | LPAM-1 (Integrin a4b7) Antibody from BIOLEGEND |
Product Specific References | n/a |
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