| 产品详情 |
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| Product Name | NIK, CT, Blocking Peptide |
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| Description | Purified. Peptide corresponding to aa931-947 of human NIK. Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFa, LPS and mitogens. A serine/threonine protein kinase which mediates NF-kB activation by IL-1, TNFa and CD95 was identified recently and designated NIK (for NF-kB inducing kinase). NIK is an activator of IkB kinase alpha and beta (IKKa and IKKb). Therefore, NIK is a key molecule in the NF-kB signaling pathway leading to the induction of a variety of gene expression in response to proinflammatory cytokines and bacteria products. Human immunodeficiency virus (HIV) and related virus require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor fami |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | NIK, CT, Blocking Peptide (NF-kappa-beta-inducing Kinase, HsNIK, FTDCR1B, HS, Mitogen-activated Protein Kinase Kinase Kinase 14, MAP3K14, Serine/threonine Protein Kinase NIK) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | N2567P |
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| Price | |
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| Order / More Info | NIK, CT, Blocking Peptide from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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