| 产品详情 |
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| Product Name | SCH-529704 |
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| Description | SCH-529074 is a small molecule activator of mutant p53. It binds specifically to the p53 DBD (DNA binding domain) in a saturable manner with an affinity of 1-2 µM. Binding restores wild type function to many oncogenic mutant forms of p53. SCH-529074 reactivates mutant p53 by acting as a chaperone. In addition to reactivating mutant p53, SCH-529074 binding inhibits ubiquitination of p53 by HDM2. MW: 563.56. Purity ≥98% |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N3-[2-[[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]methyl]-4-quinazolinyl]-N1,N1-dimethyl-1,3-propanediamine |
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| Gene, Accession, CAS # | CAS: 922150-11-6 |
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| Catalog # | 9438-5 |
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| Price | |
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| Order / More Info | SCH-529704 from BIOVISION, INC. |
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| Product Specific References | n/a |
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