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| Product Name | ONO 6818 |
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| Description | High affinity and selective human neutrophil elastase 1 (HNE1) inhibitor (Ki = 12 nM). Exhibits >100-fold less activity at other related proteases including trypsin, pancreatic elastase, collagenase and murine macrophage elastase. Inhibits HNE-induced lung hemorrhaging and suppresses leukocyte levels in an in vivo model of COPD. Orally active. Purity 98%. MW (observed): 452.51 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-Amino-N-[1-[[5-(1,1-dimethylethyl)-1,3,4-oxadiazol-2-yl]carbonyl]-2-methylpropyl]-6-oxo-2-phenyl-1(6H)-pyrimidineacetamide |
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| Gene, Accession, CAS # | CAS: 208848-19-5 |
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| Catalog # | 5651/10 |
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| Price | |
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| Order / More Info | ONO 6818 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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