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Product Name | Galectin-3 ELISA |
Description | Galectin-3 is a 26kDa -galactoside-binding protein belonging to the Galectin family, which consists of more than ten members. Galectin-3 is composed of a carboxyl-terminal carbohydrate recognition domain (CRD) and amino-terminal tandem repeats. Galectin-3 normally distributes in epithelia of many organs and various inflammatory cells, including macrophages as well as dendritic cells and Kupfer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation and cell differentiation and through transactivation by viral proteins. Galectin-3 has been shown to function through both intracellular and extracellular actions. It is a component of heterogeneous nuclear ribonuclear protein (hnRNP), a factor in pre-mRNA splicing and has been found to control cell cycle and prevent T-cell apoptosis through interaction with the Bcl-2 family members. On the other hand, this protein, which is secreted from monocytes/macrophages and epithelial cells has been demonstrated to function as an extracellular molecule in activating various types of cells such as monocytes/macrophages, mast cells, neutrophils and lymphocytes. Galectin-3 has been shown to mediate cell-cell and cell-extracellular matrix interactions and acts as a novel chemoattractant for monocytes and macrophages. Sample Types: Human cell culture, citrate plasma, EDTA plasma, heparin plasma, serum. Sample Size: 50 µL. Range: 0.47 - 30.0 ng/mL. Sensitivity: 0.29 ng/mL. Time: 3hr 10min |
Size | 96 wells |
Concentration | n/a |
Applications | Immunoassays. Research Use Only. Not for Use in Diagnostic Procedures. |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | 61-GALHU-E01 |
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Order / More Info | Galectin-3 ELISA from ALPCO |
Product Specific References | n/a |
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