| 产品详情 |
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| Antigenic Specificity | CD8a |
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| Clone | 53-6.7 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, κ |
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| Format | Brilliant Violet 650™ conjugate |
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| Size | 125 µl |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Brilliant Violet 650™ anti-mouse CD8a. CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck. |
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| Immunogen | Mouse thymus or spleen |
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| Other Names | T8, Lyt2, Ly-2 |
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| Gene, Accession # | Gene ID: 12525 |
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| Catalog # | 100741 |
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| Price | |
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| Order / More Info | CD8a Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 16116223,16263755,17000726,18003887,18337574,18390836,18490467,18784371,18941215,19017956,19318495,19542448,19752183,20008304,20211938,20562261,21276089,25819159 |
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