产品详情 |
Edit |   |
Antigenic Specificity | CD8a |
Clone | QA17A07 |
Host Species | Recombinant Mouse |
Reactive Species | mouse |
Isotype | IgG1, κ |
Format | fluorescein (FITC) conjugate |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | FITC anti-mouse CD8a Recombinant. CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck. |
Immunogen | Mouse thymus or spleen |
Other Names | T8, Lyt2, Ly-2 |
Gene, Accession # | Gene ID: 12525 |
Catalog # | 155003 |
Price | |
Order / More Info | CD8a Antibody from BIOLEGEND |
Product Specific References | n/a |
产品资料 |
|
|