产品详情 |
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Product Name | CCG-232601 |
Description | An inhibitor of the Rho/MRTF/SRF transcriptional pathway; a derivative of CCG-203971; inhibits MRTF-dependent transcription in HEK293T cells (IC50 = 0.55 µM in a luciferase reporter assay); reduces expression of α-SMA in TGF-β-stimulated human dermal fibroblasts to 31% of control at 10 µM; inhibits increases in dermal thickness and hydroxyproline content in a mouse model of bleomycin-induced dermal fibrosis at 50 mg/kg |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | CCG232601 CCG203971 HEK-293T TGFβ |
Gene, Accession, CAS # | CAS: 1922099-21-5 |
Catalog # | 24382-5 |
Price | |
Order / More Info | CCG-232601 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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