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Product Name | PQBP1, 1-265aa, Human, His tag, E.coli |
Description | Purity: > 95% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 1mM DTT. Polyglutamine binding protein 1, also known as PQBP1, is a transcription repressor that associates with polyglutamine tract-containing transcription regulators and causative genes for neurodegenerative disorders. PQBP-1 localizes to the nucleus and is present in neurons throughout the brain, with abundant levels in hippocampus, cerebellar cortex and olfactory bulb. PQBP-1 contains a WWP/WW domain that binds proline-rich motifs and a C2 domain that can influence Ca2+-dependent phospholipid signaling. Recombinant human PQBP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Size | 0.5mg, 100ug, 20ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | Polyglutamine binding protein 1, MRX55, MRXS3, MRXS8, NPW38, RENS1, SHS |
Gene, Accession, CAS # | NP 005701 |
Catalog # | ATGP1540 |
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Order / More Info | PQBP1, 1-265aa, Human, His tag, E.coli from ATGen |
Product Specific References | n/a |
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