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| Product Name | Recombinant Human LT-α (TNF-β) |
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| Description | LT-α, also known as TNF-β, is a potent mediator of inflammatory and immune responses. It belongs to the TNF superfamily of ligands and signals through TNFR1 and TNFR2. LT-α is produced by activated T and B lymphocytes, and has similar activities to TNF-α. Like TNF-α, LT-α (TNF-β) is involved in the regulation of various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. LT-α is secreted as a soluble polypeptide, but can form heterotrimers with LT-β, which effectively anchors the LT-α to the cell surface. LT-α is cytotoxic to a wide range of tumor cells. Recombinant human LT-α is secreted 171 amino acid protein (18.6 kD) which forms an active non-disulfide linked homotrimer structure in solution. |
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| Size | 20 µg |
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| Concentration | n/a |
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| Applications | ELISA, BA |
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| Other Names | Tumor necrosis factor-β, Lymphotoxin-α (LT- α), Coley's toxin, Hemorrhagic factor, Necrosin, Natural killer cytotoxic factor (NKCF), Differentiation inducing factor (DIF), TNFSF-1 |
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| Gene, Accession, CAS # | Gene ID: 4049 |
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| Catalog # | 562604 |
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| Order / More Info | Recombinant Human LT-α (TNF-β) from BIOLEGEND |
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| Product Specific References | n/a |
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