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Product Name | trans-Resveratrol |
Description | A polyphenolic phytoalexin found in a variety of plants; has anti-inflammatory, antioxidant, and anticancer activities; inhibits the cyclooxygenase and hydroperoxidase activities of COX-1 (EC50s = 15 and 3.7 µM, respectively), but not COX-2 (EC50s = >100 µM and 85 µM, respectively); inhibits carrageenan-induced paw edema in mice at 3 and 8 mg/kg; inhibits free radical formation in HL-60 human promyelocytic leukemia cells induced by TPA (EC50 = 27 µM); reduces both the incidence and number of tumors in a two-stage mouse model of skin cancer induced by TPA and DMBA at 1-25 µmol; activates SIRT1 by 8-fold in vitro at 200 µM; inhibits ERK1, JNK1, Src, PKCα, aromatase/CYP19, and DNA polymerases α and δ (IC50s = 37, 50, 20, in vitro and/or ex vivo; prolongs lifespan in model organisms including C. elegans, D. melanogaster, and mice |
Size | 250 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (E)-Resveratrol |
Gene, Accession, CAS # | CAS: 501-36-0 |
Catalog # | 70675-250 |
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Order / More Info | trans-Resveratrol from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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