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Product Name | NF-κB Inhibitor, SN50 |
Description | This peptide contains the nuclear localization sequence (NLS residues 360-369) of the transcription factor NF-κB p50 linked to a peptide cell-permeablization sequence, the hydrophobic region (h-region) of the signal peptide of Kaposi fibroblast growth factor (K-FGF). SN50 inhibits translocation of the NF-κB active complex into the nucleus. In mouse endothelial LE-II cells induced with LPS, inhibition of NF-κB nuclear translocation was 88% at 50 µg/ml (18 µM). In human monocytic THP-1 cells induced by LPS or TNFα there was 85% inhibition at 100 µg/ml. MW: 2781.5. Purity ≥97% by HPLC |
Size | 500 µg |
Concentration | n/a |
Applications | n/a |
Other Names | SN50; AAVALLPAVLLALLAPVQRKRQKLMP |
Gene, Accession, CAS # | CAS: 213546-53-3 |
Catalog # | 2506-500 |
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Order / More Info | NF-κB Inhibitor, SN50 from BIOVISION, INC. |
Product Specific References | n/a |
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