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Product Name | PU 02 |
Description | A selective 5-HT3 receptor antagonist (IC50s = 0.36-1.3 µM for human 5-HT3A, 5-HT3AB, 5-HT3AC, and 5-HT3AE in a FLIPR membrane potential assay); selective for 5-HT3 over other Cys-loop containing receptors (IC50 values >100 µM for mouse, rat, and human nAChRs, human GABAARs, and human GlyRs; inhibits 5-HT-induced currents in COS-7 cells expressing human 5-HT3A (IC50 = 0.49 µM); reduces growth of HepG2 cells in a dose-dependent manner , |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | PU02 5HT 5HT3 5HT3A 5HT3AB 5HT3AC 5HT3AE HEK-293 GABA-A COS7 Hep-G2 acetylcholine γ?aminobutyric Fluorometric Imaging Plate Reader GlyR nAChR |
Gene, Accession, CAS # | CAS: 313984-77-9 |
Catalog # | 14312-50 |
Price | |
Order / More Info | PU 02 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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