产品详情 |
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Antigenic Specificity | NK-1.1 |
Clone | PK136 |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | Brilliant Violet 421™ conjugate |
Size | 500 µl |
Concentration | n/a |
Applications | Flow Cytometry (FC), Immunofluorescence Microscopy (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Brilliant Violet 421™ anti-mouse NK-1.1. NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers. |
Immunogen | NK-1+ cells from mouse spleen and bone marrow |
Other Names | NKR-P1C, NKR-P1B, Ly-55, CD161b, CD161c, NK1.1 |
Gene, Accession # | Gene ID: 17059 |
Catalog # | 108732 |
Price | |
Order / More Info | NK-1.1 Antibody from BIOLEGEND |
Product Specific References | PubMed: 18523245,19299918,20211938,24713481 |
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