| 产品详情 |
| Edit |   |
|---|
| Product Name | LMIR5, Fc Chimera, Recombinant, Mouse |
|---|
| Description | Purity ~90% (SDS-PAGE). LMIR5, also known as CD300LB, CLM-7, and IREM-3, is a 26kD-32kD glycoprotein member of the immunoglobulin superfamily. Mouse LMIR5 consists of a 140aa extracellular domain (ECD) with one Ig-like V-type domain, a 21aa transmembrane segment, and a 31aa cytoplasmic domain. Within the ECD, mouse LMIR5 shares 51% and 86% aa sequence identity with human and rat LMIR5, respectively. The transmembrane segment contains a positively charged lysine which enables the association of LMIR5 with DAP12, DAP10, and potentially other adaptor proteins. The cytoplasmic domain of human LMIR5 contains a phosphorylatable tyrosine motif, while that of mouse LMIR5 does not. LMIR5 is expressed on the surface of myeloid lineage cells. It forms noncovalent cis-homodimers and cis-heterodimers with other CD300 family proteins, and the composition of these dimers affects the cellular response. Antibody cross-linking of LMIR5 induces mast cell granule release and cytokine production as well as |
|---|
| Size | 50ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | LMIR5, Fc Chimera, Recombinant, Mouse (CD300LB, CMRF35-like Molecule 7, CLM-7, CD300 Antigen-like Family Member B, Immune Receptor Expressed on Myeloid Cells 3, IREM-3, Leukocyte Mono-Ig-like Receptor 5, Cd300lb, Irem3) |
|---|
| Gene, Accession, CAS # | SwissProt: Q3U497 |
|---|
| Catalog # | L3189-85 |
|---|
| Price | |
|---|
| Order / More Info | LMIR5, Fc Chimera, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|