| 产品详情 |
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| Antigenic Specificity | CD150 (SLAM) |
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| Clone | TC15-12F12.2 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, λ |
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| Format | PE-Dazzle™ 594 conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PE/Dazzle™ 594 anti-mouse CD150 (SLAM). CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies. |
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| Immunogen | Mouse SLAM-human IgG1 fusion protein |
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| Other Names | SLAM, IPO-3, Signaling Lymphocyte Activation Molecule |
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| Gene, Accession # | Gene ID: 27218 |
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| Catalog # | 115936 |
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| Price | |
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| Order / More Info | CD150 (SLAM) Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 16569764,16940424,17237411,17360942,17406558,18499897,19443245,20110425,20421392 |
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