| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD150 (SLAM) |
|---|
| Clone | TC15-12F12.2 |
|---|
| Host Species | Rat |
|---|
| Reactive Species | mouse |
|---|
| Isotype | IgG2a, λ |
|---|
| Format | purified |
|---|
| Size | 500 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry (FC), IP |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Purified anti-mouse CD150 (SLAM). CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies. |
|---|
| Immunogen | Mouse SLAM-human IgG1 fusion protein |
|---|
| Other Names | SLAM, IPO-3, Signaling Lymphocyte Activation Molecule |
|---|
| Gene, Accession # | Gene ID: 27218 |
|---|
| Catalog # | 115902 |
|---|
| Price | |
|---|
| Order / More Info | CD150 (SLAM) Antibody from BIOLEGEND |
|---|
| Product Specific References | PubMed: 16569764,16940424,17237411,17360942,17406558,18499897,19443245,20110425,20421392 |
|---|
| 产品资料 |
|
|