产品名称 Protein Arginine Methyltransferase 1 (PRMT1) protein (His tag,MBP tag) from ANTIBODIES-ONLINE GmbH
产品货号 ABIN805574
产品价格 现货询价,电话:010-67529703
产品规格 50 µg
产品品牌 ANTIBODIES-ONLINE GmbH
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Product NameProtein Arginine Methyltransferase 1 (PRMT1) protein (His tag,MBP tag)
DescriptionPRMT1 Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in a glycine and arginine-rich domain (may methylate HNRNPA1 and histones). Methylates SUPT5H.The PRMT1 protein functions as a histone methyltransferase specific for H4.PRMT1 is an essential factor in oncogenesis and is a potential novel therapeutic target in cancer.PRMT1-mediated methylation serves as a positive modulator of IR/IRS-1/PI3K pathway and glucose uptake in skeletal muscle cells. CAF1 is a new regulator of PRMT1-dependent arginine methylation.PRMT1 arginine-methylates MRE11 therefore it regulates the activity of MRE11-RAD50-NBS1 complex during the intra-S-phase DNA damage checkpoint response.PRMT1 plays a post-translationally part in regulating the transcriptional activity.PRMT1 is found predominantly in the cytoplasma though a fraction of PRMT1 is located in the nucleus Synonyms: ANM1, HCP1, HRMT1L2, IR1B4, Interferon receptor 1-bound protein 4, EC 2.1.1, Protein arginine N-methyltransferase 1, PRMT1, HMT2
Size50 µg
Concentrationn/a
Applicationsn/a
Other NamesARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 1A|ATPRMT1A|F6F22.30|F6F22_30|protein arginine methyltransferase 1A|prmt1|DDBDRAFT_0183976|DDBDRAFT_0235399|DDB_0183976|DDB_0235399|PRMT1|DKFZp459J1326|ANM1|HCP1|HRMT1L2|IR1B4|fb39h07|hrmt1l2|wu:fb39h07|zf1|zgc:66201|3E10|Hrmt1l2|anm1|hcp1|ir1b4|xPRMT1|xPRMT1b|6720434D09Rik|AW214366|Mrmt1
Gene, Accession, CAS #Gene ID: 3276
Catalog #ABIN805574
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Order / More InfoProtein Arginine Methyltransferase 1 (PRMT1) protein (His tag,MBP tag) from ANTIBODIES-ONLINE GmbH
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