| 产品详情 |
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| Product Name | Recombinant Mouse CCL19 (MIP-3β) (carrier-free) |
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| Description | CCL19 is a CC chemokine expressed in lymph nodes. CCL19 is only 32% identical to CCL21 at the amino acid level; nevertheless, these chemokines bind to the same receptor: CCR7. CCL19 is not expressed in high endothelial venules (HEV) as CCL21, but CCL19 is transcytosed in HEV. It has been described that CCL19 binds to CCX-CKR and CRAM-B receptors. These two receptors are members of the non classical chemokine receptor family which, in addition, includes D6, DARC, and CXCR7. CCX-CKR has been suggested to be a scavenging receptor for CCL19, and CRAM-B receptor might be responsible for the transcytosis in HEV for CCL19. In addition, CRAM recycles constitutively, and can internalize CCL19 within a few minutes, suggesting an implication in the regulation of immune responses and homing processes. |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | BA |
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| Other Names | EBI1 ligand chemokine (ELC), Macrophage inflammatory protein-3-beta (MIP-3b), Small inducible cytokine subfamily A, member 19 (SCYA19), MIP3b, MIP3 beta, MIP 3 beta |
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| Gene, Accession, CAS # | Gene ID: 24047 |
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| Catalog # | 587806 |
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| Order / More Info | Recombinant Mouse CCL19 (MIP-3β) (carrier-free) from BIOLEGEND |
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| Product Specific References | n/a |
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