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| Product Name | Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 2-382) protein |
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| Description | Protein Phosphatase 1A (PPM1A) is a member of the PP2C family of Ser/Thr protein phosphatases which are known to be negative regulators of cell stress response pathways. PPM1A has a broad specificity. PPM1A negatively regulates the activities of MAP kinases and MAP kinase kinases. Also, it negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. In addition, PPM1A can dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control.Alternative Names: Protein Phosphatase 1A, Protein Phosphatase 2C Isoform Alpha, PP2C-Alpha, Protein Phosphatase IA, PPM1A, PPPM1A |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2310003C21Rik|2900017D14Rik|AI427932|AU017636|MMPa-2|MPPa-1|PP2C-ALPHA|PP2CA|PP2Calpha|Pp2c1|pp2c-alpha|pp2ca|pp2calpha|pp2ca2|fc18g04|ppm1a|wu:fc18g04|zgc:92329 |
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| Gene, Accession, CAS # | Gene ID: 5494 |
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| Catalog # | ABIN1097374 |
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| Order / More Info | Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 2-382) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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