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Product Name | Human CellExp™ HGFR/c-MET, human recombinant |
Description | Hepatocyte growth factor receptor (HGFR), also known as mesenchymal-epithelial transition factor (MET), c-Met, and is a glycosylated receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. HGFR protein possesses tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. HGFR is normally expressed by cells of epithelial origin, while expression of HGF is restricted to cells of mesenchymal origin. Upon HGF stimulation, HGFR induces several biological responses that collectively give rise to a program known as invasive growth. Abnormal HGFR activation in cancer |
Size | 20 µg |
Concentration | n/a |
Applications | RUO |
Other Names | MET, AUTS9, HGFR, RCCP2, c-Met |
Gene, Accession, CAS # | MET, Gene ID: 4233, Accession: P08581 |
Catalog # | 7393-20 |
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Order / More Info | Human CellExp™ HGFR/c-MET, human recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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