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| Product Name | Human CellExp™ HMGB1 /HMG1, human recombinant |
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| Description | High-mobility group protein B1 (HMGB1), also known as high-mobility group protein 1 (HMG-1) and amphoterin, is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3. HMGB1 is a non-histone architectural chromosomal protein ubiquitously present in all vertebrate nuclei and binds double-stranded DNA without sequence specificity. It is also involved in inflammation and damage by binding to TLR4, which mediates HMGB1-dependent activation of macrophage cytokine release. This positions HMGB1 at the intersection of sterile and infectious inflammatory responses. HMGB1 has been studied as a DNA vaccine adjuvant and a target for cancer therapy. MW: 25 kDa. Purity ≥95% |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | HMGB1, HMG1, HMG3, SBP-1 |
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| Gene, Accession, CAS # | HMGB1, Gene ID: 3146, Accession: P09429 |
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| Catalog # | 7240-10 |
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| Order / More Info | Human CellExp™ HMGB1 /HMG1, human recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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