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| Product Name | Human CellExp™ ICOS / CD278, Fc Tag, Human recombinant |
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| Description | Inducible T-cell costimulator (ICOS) is also known as Activation-inducible lymphocyte immunomediatory molecule (AILIM), CD278, which belongs to the CD28 family of immune costimulatory receptors consisting of CD28, CTLA-4 and PD-1. ICOS enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. CD278 / ICOS prevents the apoptosis of pre-activated T-cells and also plays a critical role in CD40-mediated class switching of immunoglobin isotypes. This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 40.2 kDa. The protein migrates as 46-55 kDa u |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | ICOS, CD278, AILIM, Inducible T-cell costimulator |
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| Gene, Accession, CAS # | CD278, Gene ID: 29851, Accession: NP_036224 |
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| Catalog # | P1378-10 |
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| Order / More Info | Human CellExp™ ICOS / CD278, Fc Tag, Human recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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