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Product Name | Human CellExp™ ICOSLG /B7-H2 /CD275, human recombinant |
Description | ICOS ligand (ICOSLG) is also known as B7 homolog 2 (B7-H2), B7-related protein 1 (B7RP-1) and CD antigen CD275, which belongs to the immunoglobulin superfamily and BTN/MOG family. ICOSLG contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. Isoform 1 is widely expressed, while isoform 2 is detected only in lymph nodes, leukocytes and spleen. B7-H2 is ligand for the T-cell-specific cell surface receptor ICOS. B7-H2 acts as a costimulatory signal for T-cell proliferation and cytokine secretion and induces also B-cell proliferation and differentiation into plasma cells. B7-H2 could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modula |
Size | 20 µg |
Concentration | n/a |
Applications | RUO |
Other Names | ICOSLG, B7-H2, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, LICOS, ICOS ligand. |
Gene, Accession, CAS # | ICOSLG, Gene ID: 23308, Accession: O75144 |
Catalog # | 7426-20 |
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Order / More Info | Human CellExp™ ICOSLG /B7-H2 /CD275, human recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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