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| Product Name | Human CellExp™ IL-17A, Human Recombinant |
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| Description | Interleukin-17 is a proinflammatory cytokine produced by activated T cells. IL-17 regulates the activities of NF-kappa B and mitogen-activated protein kinases. IL17 can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. The original described IL-17 protein, now known as IL-17A, was identified from a CD4+ T cells DNA library. IL-17 can be induced from primary peripheral blood CD4+ T cells upon stimulation. Supernatant from cells transfected with IL-17 induced IL-16 and IL-18 production and enhanced the surface expression of the |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | CTLA-8, IL-17, IL-17A, Cytotoxic T-lymphocyte-associated antigen 8. |
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| Gene, Accession, CAS # | IL17A, Gene ID: 3605, Accession: Q16552 |
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| Catalog # | 6468-50 |
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| Order / More Info | Human CellExp™ IL-17A, Human Recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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