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| Product Name | Human CellExp™ IL-28A, Human Recombinant |
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| Description | IL-28A is distantly related to type I interferons and the IL-10 family. Expression of IL-28A is induced by viral infection which interacts with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha. IL-28A exhibits common features with type I IFNs such as antiviral activity, antiproliferative activity and in vivo antitumor activity. They act similarly to IFNs, but are less effective generally and have activity in a more limited range of cell lines. IL-28A induces ELR (-) CXC chemokine mRNA in human peripheral blood mononuclear cells, in an IFN-gamma-independent manner. It is able to generate tolerogenic DCs, an activity that could thwart IFN-beta functions. IL-2 |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Interleukin-28A, IL-28A, IFN-Lambda 2, Interferon-Lambda 2, Cytokine ZCYTO20, IL28A, IFNL2, ZCYTO20. |
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| Gene, Accession, CAS # | IFNL2, Gene ID: 282616, Accession: Q8IZJ0 |
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| Catalog # | 6471-50 |
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| Order / More Info | Human CellExp™ IL-28A, Human Recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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