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Product Name | NNT-1/BCSF-3, Human Recombinant |
Description | NNT-1/BCSF-3 is a neurotrophic factor with B-cell stimulating capabilities. Expressed in lymph nodes and spleen, NNT-1/BCSF-3 binds and activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member β (LIFR-β) and induces tyrosine phosphorylation of these receptors. In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss and B cell hyperplasia associated with increased in serum IgG and IgM. Human Recombinant NNT-1/BCSF-3 is a 22.4 kDa protein containing 199 amino acid residues. MW: 22.4 kDa. Purity ≥ 98.0% |
Size | 2 µg |
Concentration | n/a |
Applications | RUO |
Other Names | Novel Neurtrophin-1, NNT-1, B-Cell-Stimulating Factor-3, BSF-3, Cardiotrophin-like cytokine, Cardiotrophin-like cytokine factor 1 (CLCF1), CLCF1, BSF3, CLC, NNT1 |
Gene, Accession, CAS # | CLCF1, Gene ID: 23529, Accession: Q9UBD9 |
Catalog # | P1332-2 |
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Order / More Info | NNT-1/BCSF-3, Human Recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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