| 产品详情 |
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| Product Name | RVX-208 |
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| Description | A selective antagonist of BET bromodomains, binding with 10-100-fold higher affinity for BD2 (IC50 = 0.04-0.28 µM) over BD1 (IC50 = 1.8-3.1 µM), which causes selective release of BET proteins from chromatin; increases the expression of ApoA1 and reduces atherosclerosis in hyperlipidemic ApoE-deficient mice |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | epigenetics atherosclerosis proteins bindings chromatins research BD1 BD2 BDs 1 2 ones twos BD-1 BD-2 RVXs RVX208 208 bromodomains selective antagonists BETs cells apolipoproteins ApoA1 A1 mice mouse monkeys humans hyperlipidemic ApoE deficient deficiency deficiencies 1246400-89-4 1431550-07-0 RVX 000222 biochemicals |
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| Gene, Accession, CAS # | CAS: 1044870-39-4 |
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| Catalog # | 16424-10 |
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| Price | |
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| Order / More Info | RVX-208 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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