| 产品详情 |
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| Product Name | Lin28-TAT, Human Recombinant |
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| Description | Translational enhancer' that drives specific mRNAs to polysomes and increases the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in mRNA stabilization. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression. Suppressor of microRNA (miRNA) biogenesis, including that of let-7, miR107, miR-143 and miR-200c. Specifically binds miRNA precursors (pre-miRNAs), recognizing an 5'-GGAG-3' motif found in pre-miRNA terminal loop, and recruits ZCCHC11/TUT4 uridylyltransferase. T |
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| Size | 20 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | CSDD1, LIN28A, ZCCHC1, Protein lin-28 homolog A, Zinc finger CCHC domain-containing protein 1 |
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| Gene, Accession, CAS # | LIN28A, Gene ID: 79727, Accession: Q9H9Z2 |
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| Catalog # | P1010-20 |
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| Order / More Info | Lin28-TAT, Human Recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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