Microfluidic Chips

SynVivo-Chip

Microfluidic Chips

SynVivo is a cell based microfluidic chip that enables shorter and more successful drug development by combining the efficiency and control of in vitro testing with the realism and validation of in vivo studies. SynVivo biochips are readily available as standard stock items. We are also capable of producing any custom designed chip and morphology as needed.

The SynVivo platform can support custom assays based on your research application. Don’t see a catalog assay for your biological question? Want to perform your assay using a linear chip design? We can develop a custom assay kit for you using our library of chip designs- See more information in the following tabs.

Linear Channels
Bifurcating Channels
Microvascular Networks
Idealized Networks

Custom Designs – If you need a specialized microvasulature or other design we have the necessary equipment to fabricate most any design based on your research needs. Our engineers will work with you to help design the most relevant SynVivo channel or network configuration to help you achieve your research goals.

Use Linear Channels for studying cell/particle adhesion and cell-cell or cell-particle interactions at the micro-circulation scale. Use as a substitute for parallel plate flow chambers for >90% savings in consumables.

Linear Channels Design Library

Three channels per chip of various widths to allow you to study shear effects based on channel size and flow rates.

IMN1-LC

Standard Width Options (W1 / W2 / W3):

100 μm / 100 μm / 100 μm
250 μm / 250 μm / 250 μm
500 μm / 500 μm / 500 μm
100 μm / 250 μm / 500 μm

Custom designs/sizes also available.

Cat#

Product Name

Price

101001

Linear Channel Chip (3×100μm)

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101002

Linear Channel Chip (3×250μm)

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101003

Linear Channel Chip (3×500μm)

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101004

Linear Channel Chip (100/250/500μm)

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Note: Does not include other required consumables such as tubing, clamps, syringes, needles, cells, media and matrix.
Laboratory equipment required includes incubators, inverted microscopes, and syringe pumps.

Use symmetric and asymmetric bifurcations to study cell/particle adhesion and cell-cell or cell-particle interactions at bifurcations and to study the effect of the bifurcation angle and asymmetry on adhesion. Compare adhesion in linear sections and bifurcations simultaneously.

Bifurcating Channels Design Library

With various options of symmetric and asymmetric bifurcating angles and parent/daughter channel widths you can likely find a set of designs to provide you the best models for your research.

IMN1-BC

Standard Symmetric Bifurcation Angle (θ_B/θ_C) Options:

15° + 15°
30° + 30°
45° + 45°
60° + 60°

Custom designs/sizes also available.

Cat#

Product Name

Price

101005

Bifurcating Channel Chip (30° Sym)

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101006

Bifurcating Channel Chip (60° Sym)

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101007

Bifurcating Channel Chip (90° Sym)

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101008

Bifurcating Channel Chip (120° Sym)

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By incorporating natural tissue regions within the network topology, the co-culture networks allow study of cell and drug behavior at and across the interfaces. The co-culture network constructs are available with several options for channel size, tissue region scaffolding, and barrier design. We can help you select the right parameters for your needs and can also construct custom designs if needed.