Athens Research & Technology;16-16-161213-L;Plasmin, Human Plasma, Lyophilized

品牌:athens research & technology

Athens Research & Technology 公司位于美国乔治亚州雅典市,从1986年以来一直致力于纯化高纯度,高活性的人类蛋白质和开发这些蛋白的多克隆抗血清。我们的常规产品包括丝氨酸蛋白酶、蛋白酶抑制剂、中性粒细胞酶、载脂蛋白、脂蛋白,血小板蛋白、转铁蛋白、免疫球蛋白等。二十年多年来,世界各地的研究人员都在使用我们公司的产品。在炎症、冠状动脉疾病、自身免疫性疾病、癌症、老年痴呆症等等研究的主要科学出版物中都能看到引用我们公司的产品。
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MW: 81,000
Extinction Coefficient: 1.71

Lyophilized from 20 mM NaP04, pH 7.4, with 10 mg/ml D-Mannitol and 10 mg/ml NaCl.

Plasmin functions in fibrinolysis, fibrinogenolysis, as well as in the complement cascade. This protease has been prepared by using streptokinase to activate human plasma plasminogen.

Minimum Activity: 15 units/mg protein One unit is defined as the amount of enzyme that hydrolyzes one umole of tosyl-Gly-Pro-Lys-pNA oer minute at 25oC, pH 7.8. Note: One unit=1.25 CU.

Storage: -20°C

Synonym: Fibrinolysin

Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Athens Research & Technology products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research or further manufacturing use only.

Product Citations:
Li, Qun, Tatiana Syrovets, Thomas Simmet, Jiazeng Ding, Jianzhong Xu, Wendong Chen, Dingliang Zhu, and Pingjin Gao. "Plasmin induces intercellular adhesion molecule 1 expression in human endothelial cells via nuclear factor-κB/mitogen-activated protein kinases-dependent pathways.Experimental Biology and Medicine 238, no. 2 (2013): 176-186.
Li, Qun, Yves Laumonnier, Tatiana Syrovets, and Thomas Simmet. "Recruitment of CCR6-expressing Th17 cells by CCL20 secreted from plasmin-stimulated macrophages". Acta biochimica et biophysica Sinica(2013).

Shuster, Katherine A., Shirley K. Wrobleski, Angela E. Hawley, Benedict R. Lucchesi, Dorothy R. Sorenson, Ingrid L. Bergin, Robert E. Sigler et al. "Prothrombotic Effects of Thrombolytic Therapy in a Rat (Rattus norvegicus) Model of Venous Thrombolysis.Comparative medicine 63, no. 3 (2013): 244-251.