Athens Research & Technology;16-16-032001;Transferrin (HOLO), Human Plasma

型号:16-16-032001
联系人:程园
联系电话:18611717737
品牌:athens research & technology


Athens Research & Technology 公司位于美国乔治亚州雅典市,从1986年以来一直致力于纯化高纯度,高活性的人类蛋白质和开发这些蛋白的多克隆抗血清。我们的常规产品包括丝氨酸蛋白酶、蛋白酶抑制剂、中性粒细胞酶、载脂蛋白、脂蛋白,血小板蛋白、转铁蛋白、免疫球蛋白等。二十年多年来,世界各地的研究人员都在使用我们公司的产品。在炎症、冠状动脉疾病、自身免疫性疾病、癌症、老年痴呆症等等研究的主要科学出版物中都能看到引用我们公司的产品。
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MW: 80,000

Lyophilized from 20 mM Na Phosphate, pH 7.4, and 150 mM NaCl


Transferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100 ml. The specific iron-binding protein in plasma, it has a role in the transportation and distribution of iron among the body organs, in iron metabolism and prevention of iron loss via the kidneys. Stored in bone marrow as Tf-bound iron, it also possesses bacteriostatic and fungistatic activity. Clinically, decreases in transferrin are observed in congenital disorders, newborns, inflammatory diseases, hypoproteinemias and nephrotic syndrome; increases are found in pregnancy, iron-deficiency anemias, and inoculation hepatitis. Transferrin is required by all types of cells in cultures for maximal growth. It is, therefore, an important transport factor used in defined culture media.


Storage: -20°C

Purity: >=95% by SDS-PAGE

Iron Content: >= 1100 ug per gram

Synonym: Human transferrin, Siderophilin

Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Athens Research & Technology products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research use only.


Citations: 
Enns, Caroline A., Riffat Ahmed, Jiaohong Wang, Akiko Ueno, Christal Worthen, Hidekazu Tsukamoto, and An-Sheng Zhang. "Increased Iron Loading Induces Bmp6 Expression in the Non-Parenchymal Cells of the Liver Independent of the BMP-Signaling Pathway." PloS one 8, no. 4 (2013): e60534.


Ref: 
MacGillivray, R.T.A. et al. 1982 Proc. Natl. Acad. Sci. USA. 79,2504; Rivat,C. et al. 1992 J. Chromatogr. 576,71