美国IITC甩尾测痛仪,Tail Flick Test Analgesia Meter for Mice and Rats

型号:甩尾测痛仪
联系人:李胜亮
联系电话:18618101725
品牌:iitc


美国IITC甩尾测痛仪,Tail Flick Test Analgesia Meter for Mice and Rats


甩尾测痛仪(疼痛甩尾测试,甩尾仪,Tail Flick Test Analgesia Meter Apparatus(测试动物疼痛反应时间和动物对镇痛药物的疼痛反应极限,使用简便,更多详情敬请来电咨询)

 

疼痛甩尾测试仪用于测试动物疼痛反应时间和动物对镇痛药物的疼痛反应极限实验过程中检测到动物尾部甩动后内置的计时器自动停止计时

 

The Tail Flick Test apparatus meter measures latency and/or temperature threshold when detecting properties of narcotic and strong non-narcotic drugs on mice and rats. A built-in Timer is automatically stopped when the animals’ tail flicks out of the beam of light, test result will be displayed on readout for viewing.

An overhead halogen light source is in a constant “ON” (idle state). A pre-focused heat source supplies an area of 4X6mm stimulation to the tail. A built-in sensor in the tail groove detects the tail flick of the animal. The tail groove is a non-metallic material to avoid unnecessary conditioning of your animals; unlike other systems. If the animal does not flick their tail within the pre programmed cut-off time; the heat source shuts off automatically; avoiding tissue damage. Built-in timer displays the reaction time in 0.01 second increments. Control of system can be from either the front panel or supplied footswitch: Start, Stop and Reset of tests.

 

疼痛甩尾测试仪主要特点: 

 

实时尾部温度/触发可选

触发温度设置功能

精确数字控制,时间精确度为0.01

自动切断保护功能

光束强度可调节,步进量1

自动检测活动反应

强制取消定时器功能

数字显示功能

标准计算机打印口输出

RS-232输出



相关文献:

Gender-specific behavioral and immunological alterations in an animal?model?of autism induced by prenatal exposure to valproic acid

T Schneider, A Roman, A Basta-Kaim, M Kubera… - …, 2008 - Elsevier

… adverse developmental consequences produced by early brain injuries, especially in animal
models of human … valproic acid have not been studied in the presented animal model of autism …
withdrawal test carried out using an Analgesia Meter apparatus (Mod 33, IITC, INC, USA …

  

The antinociceptive effect of intrathecally administered adenosine analogs in mice correlates with the affinity for the A1-adenosine receptor

R Karlsten, C Post, I Hide, JW Daly - Neuroscience letters, 1991 - Elsevier

… The animals were used only once. Testing of tail flick was performed using an IITC Inc. Model
33 Analgesiameter, with the light focused on the tip of the tail [3]. The intensity of the beam was
adjusted to give a reaction time of 3-4 s before the it injection of the drug solutions …

Behavioral alterations in rats prenatally exposed to valproic acid: animal?model?of autism

T Schneider, R Przew?ocki - Neuropsychopharmacology, 2005 - nature.com

… The thermal paw withdrawal test was carried out using an Analgesia Meter apparatus (Mod 33,
IITC, Inc., USA) … aberrations described in this paper appear before puberty, which could distinguish the VPA rat model of autism from other animal models of psychiatric …

  

[PDF] Stress of chronic food restriction attenuates the development of adjuvant arthritis in male Long Evans rats

J Jurcovicova, M Stancikova, K Svik… - Clinical and …, 2001 - clinexprheumatol.org

… They had free access to food. In group four AA was induced and the animals received 60%
of the food consumed by the arthritic rats (group 3) on the previous day … The pain threshold
was measured using the tail flick analgesia meter (Model 33 IITC Inc …

 

Involvement of a spinal brain-derived neurotrophic factor/full-length TrkB pathway in the development of nerve injury-induced thermal hyperalgesia in mice

Y Yajima, M Narita, M Narita, N Matsumoto, T Suzuki - Brain research, 2002 - Elsevier

… each of the hind paws of mice was tested individually using a thermal stimulus apparatus (model
33 Analgesia Meter; IITC Inc./Life Science … An aliquot of tissue sample was diluted with an equal volume of electrophoresis sample buffer (Protein Gel Loading Dye-2x …

  

[HTML] Prolonged gabapentin analgesia in an experimental mouse?model?of fibromyalgia

M Nishiyori, H Ueda - Molecular pain, 2008 - molecularpain.biomedcentral.com

… 10 μg in the neuropathic pain model, which is consistent with the previous study that … the ICS model is a promising candidate for experimental FMS or generalized pain syndrome models … thermal paw withdrawal test was carried out using a thermal stimulus (Model 33 Tail Flick …

Early neonatal experience of Long-Evans rats results in long-lasting changes in morphine tolerance and dependence

M Kalinichev, KW Easterling, SG Holtzman - Psychopharmacology, 2001 - Springer

… an organism's responsiveness to stress has been exten- sively investigated in several rodent
models … Previous findings by Kehoe and Blass (1986) provide indirect evidence indicating that
maternal … a light source was focused on the lower third of the tail (Model 33, Tail Flick …


Peripheral antinociceptive effects of MC4 receptor antagonists in a rat?model?of neuropathic pain–a biochemical and behavioral study

K Starowicz, SA Mousa, I Obara, A Chocyk… - Pharmacological …, 2009 - Elsevier

… PWL) in response to noxious thermal stimuli using an Analgesia Meter (mod 33, IITC INC., Landing, NJ … The initial phase of the CCI model of neuropathic pain involves inflammation around the nerve …restricted to the dorsal horns of the spinal cord, similar to previous studies [26 …

Analgesia is produced by uterocervical mechanostimulation in rats: roles of afferent nerves and implications for analgesia of pregnancy and parturition

AR Gintzler, BR Komisaruk - Brain research, 1991 - Elsevier

… a lamp mounted 8 cm above the tail and was maintained until a response was elicited or 10 s
had elapsed (IITC Inc., Model 33, Landing, NJ) … Since in a previous study, there was no correlation between the magnitude of increase in TFL produced by vaginal stimulation and the …

  

An individual variation study of electroacupuncture analgesia in rats using microarray

YZ Gao, SY Guo, QZ Yin, T Hisamitsu… - The American journal of …, 2007 - World Scientific

… Previous studies have demonstrated that electroacupuncture (EA) at ST36 acupoint could produce profound analgesia … recording the tail flick latency (TFL) induced by radiant heat using Model 33 Tail Flick … Briefly, 750 ng of fast recovery sample cRNA were mixed with 750 ng of …

  

[PDF] Does exogenous melatonin influence the free radicals metabolism and pain sensation in rat

I Pekarkova, S Parara, V Holecek, P Stopka, L Trefil… - Physiol Res, 2001 - biomed.cas.cz

… It was found in our previous research in the field of pain that after repeated painful … The tail-flick test (TF) (Tail Flick Analgesia Meter Model 33, IITC Inc., Life Science Instruments, USA) measures the … Sample preparation On the last day of the experiment (the 5th day), after all the …

  

Direct evidence for the involvement of endogenous β-endorphin in the suppression of the morphine-induced rewarding effect under a neuropathic pain-like state

K Niikura, M Narita, M Narita, A Nakamura, D Okutsu… - Neuroscience …, 2008 - Elsevier

… paws of rats were tested individually using a thermal stimulus apparatus (model 33 Analgesia
meter … In the present study, sample preparation was performed 10 days after partial sciatic … 2B).
Consistent with many previous studies which have characterized afferent projections to …


[PDF] Antinocieptive activity of Toddalia asiatica (L) Lam. in?models?of central and peripheral pain

HN KariukiTI KanuiA YenesewNB Patel… - 2012 - inforesights.com

… Antinocieptive activity of Toddalia asiatica (L) Lam. in models of central and peripheral pain … Tail flick test A radiant heat tail-flick IITC Inc. Model 33 analgesiometer was used to measure response latencies according to the method described previously (Corrêa et al., 1996) …



Tail Flick Test Analgesia Meter for Mice and Rats

Tail Flick Analgesia MeterThe IITC Tail Flick Test apparatus meter measures latency and/or temperature threshold when detecting properties of narcotic and strong non-narcotic drugs on mice and rats. A built-in Timer is automatically stopped when the animals’ tail flicks out of the beam of light, test result will be displayed on readout for viewing.

An overhead halogen light source is in a constant “ON” (idle state). A pre-focused heat source supplies an area of 4X6mm stimulation to the tail. A built-in sensor in the tail groove detects the tail flick of the animal. The tail groove is a non-metallic material to avoid unnecessary conditioning of your animals; unlike other systems. If the animal does not flick their tail within the pre programmed cut-off time; the heat source shuts off automatically; avoiding tissue damage. Built-in timer displays the reaction time in 0.01 second increments. Control of system can be from either the front panel or supplied footswitch: Start, Stop and Reset of tests.

View Product Sheet

TAIL TEMPERATURE OPTION (T)
Tail Temperature ProbeaMeasurement of tail temperature at all times.

Trigger temperature is automatic at start of every test. Warms tail to preset temperature (set by user) and then tests start, allowing all tail temperatures to be identical.
This optional feature allows automatic preheating of the tail up to 75 degrees c., ensuring all experiment protocols to be precisely controlled and repeated. Once a preset temperature is reached, the test and timer start automatically. Once the animal reacts via tail flick the timer and heat source stop and test results are displayed. Readout will now show in repeatable sequence, start , end temperatures and test time. This unique feature stores the set temperature unless otherwise changed; eliminating temperature variations from test to test. We recommend that animals be restrained with one of the IITC restrainers.

This unit solves the problem associated with “tail temperature prior to and at the end of testing.” See article: KJELL HOLE AND ARNE TJOLSEN: The Tail-Flick Formalin Test in Rodents: Changes in Skin Temperature as a Confounding Factor. Pain 53 (1993) pages. 247-254 Elsevier).

 

Features
Tail Temperature Optional (T)
Precise programmable digital control 
Humane cut-off feature
Adjustable heat intensity in 1% increments room temperature to 250 degrees C.
Reaction is detected automatically 
Manual override of all timer functions 
Alphanumeric readout 
All Functions and parameters entered via key-pad 
Footswitch - RS232 - Printer output (standard)
Software - USB - (optional)

Dimensions:

Electronics: 18" x 18"

Two year warranty
120/240V
CE

Part #

Description

33

Tail Flick Test Analgesia Meter

33T

Tail Flick Test Analgesia Meter/Tail Temperature

18

High Intensity Bulbs, 2 per pack

Series 8

Software for Tail Flick