美国Thermo Fisher Dharmacon www.dharmacon.com
Thermo Scientific Dharmacon® 创立于1995年，是世界领先的siRNA产品供应商和RNAi技术服务商，其凭借三大技术和六类产品，建立了全新的基因沉默标准。最新统计显示，全球顶尖杂志Nature系列期刊文章中使用Dharmacon产品的数目已高达1200多篇，这一数据遥遥领先于RNAi领域内的其它品牌，奠定了其目前在RNAi研究领域无可替代的领军者地位。

三大技术：

SMARTselection™ 技术-----确保了siRNA的功能性和特异性；
SMARTpool® 技术------不用任何验证即可确保靶基因表达水平沉默至少75%；
ON-TARGETplus™ -----显著降低基因沉默中的脱靶效应，效率高达90%以上。
六类产品：

Accell™ siRNA------该产品是RNAi研究领域具革命性的一项创举，它无需任何传统介质（如转染试剂、病毒载体和电转）即可将siRNA高效递送进入任何类型细胞；
MiRIDIAN® microRNA Mimics & hairpin Inhibitors------设计先进，调节功能异常强大，实验结果高度可重复。
siGENOME™ siRNA-----四大组合，打造了全球最全面、最可靠的siRNA基因沉默平台；
DharmaFECT™ 转染试剂------五种选择，可满足siRNA对众多细胞的高效超低毒转染；
siRNA对照产品-----多个产品，提供业内最全面可靠的siRNA对照产品菜单，为成功研究基因沉默创造了良好条件；
siRNA文库------多达30条信号通路/基因家族的siRNA文库可以对整条信号通路或者整个基因家族的功能进行批量标准化的研究。
 
We are part of Thermo Fisher Scientific, the world leader in serving science. Thermo Fisher Scientific enables customers to make the world healthier, cleaner and safer by providing analytical instruments, equipment, reagents and consumables, software and services for research, analysis, discovery and diagnostics. With annual sales of more than $9 billion, Thermo Fisher Scientific has 30,000 employees and serves more than 350,000 customers in pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies as well as environmental, industrial quality and process control settings.

Dharmacon History
Dharmacon Research, Inc. was founded in 1995 by Stephen Scaringe to develop and commercialize a new technology for RNA oligonucleotide synthesis. The original Dharmacon focus and vision was to develop 2'-ACE RNA technology as the standard for RNA synthesis and to advance RNA oligo-dependent applications and technologies. When RNA interference (RNAi) emerged in the late 1990's, Dharmacon was poised to provide RNAi-related products to the multitude of academic and industry researchers. Dharmacon has become an important resource for those investigating the mechanisms of siRNA (small interfering RNA)-induced gene knockdown and applying the specificity and potency of RNAi to human biotherapeutics. Dharmacon's expertise in bioinformatics, RNA biology, and synthesis chemistry has allowed it to develop a complete line of products for the RNAi researcher, including SMARTselection™ designed siRNA and SMARTpool® siRNAs carrying a guarantee of at least 75% silencing of any specific gene, the siGENOME® siRNA collection targeting all unique genes in the human genome, and Dharmacon siRNA Libraries targeting gene families or genes involved in specific cell pathways; siRNA libraries are also available in Reverse Transfection Format.

In November of 2002, Dharmacon Research, Inc. officially changed its name to Dharmacon, Inc., to reflect the increasing capabilities and future growth potential of the company, as it had advanced beyond research and development and into whole solutions for RNA oligo-dependent applications and technologies. In March of 2004, Dharmacon became a wholly owned subsidiary of Fisher Scientific International, Inc. In November of 2006, Fisher Scientific International, Inc. merged with Thermo Electron Corporation to become Thermo Fisher Scientific.