美国MicroCal   www.microcal.com www.gelifesciences.com
MicroCal, LLC is now part of GE Healthcare.
MicroCal公司的VP-ITC等温滴定微量热仪，是迄今最灵敏的微量热仪，简便易用，高度自动化。MicroCal仪器广泛应用与世界范围内的各大制药公司，生物技术公司，高等院校，研究院所等机构内。
MicroCal was founded in 1977 with the mission to develop, manufacture and market ultrasensitive calorimeters. Prior to the formation of MicroCal, commercial calorimeters were extremely difficult to use, had long experimental times and required large amounts of sample due to poor sensitivity. As a result, the use of microcalorimetry was limited almost exclusively to specialists who devoted themselves primarily to calorimetry.
Technology and product improvements are important cornerstones of our philosophy at MicroCal. Our innovations have led to numerous advances in both microcalorimetry systems and software for the collection, analysis and presentation of calorimetric data. As a result, microcalorimetry is now among the fastest growing areas of life sciences research and MicroCal instruments are recognized across the world as the industry standard and can be found in major pharmaceutical, biotech, academic and government institutions worldwide.
MicroCal's first product was the MC-1 scanning calorimeter. This instrument quickly became the leading commercially available ultrasensitive Differential Scanning Calorimeter (DSC). In the late 1990’s, MicroCal launched the VP-DSC, the best selling ultrasensitive DSC system in the world. This was followed in 2003 with the introduction of the VP-Capillary DSC Platform, designed for high-throughput stability screening.
The scientists and engineers at MicroCal pioneered the development of a commercial Isothermal Titration Calorimeter (ITC) capable of measuring biological interactions. In 1989, MicroCal introduced the OMEGA, the first ITC system which was sensitive enough to measure heats of binding for biological interactions. Substantial improvements were made with the development of the MCS-ITC and further improvements in sensitivity and ease of use have been included in the VP-ITC and the Auto-ITC systems. In 2007, we introduced the iTC200, representing yet another leap in technology and instrument performance. In 2008 we will introduce the Auto-iTC200, a fully automated version of the iTC200.
Over the past 30 years, MicroCal has been privileged to participate in the development and advancement of an important technology that has found broad application in the basic research of biomolecules and the discovery and development of many new therapeutics and biotherapeutics. We look forward to continuing our participation and leadership in this important area of biological science and to developing important new innovations that will continue to expand the future capabilities of our technology and products. Conceiving those innovations, developing the core technology and turning those developments into advanced new products is our job, and more importantly, it is our commitment to our customers.
Our customers have rewarded us by adopting our technology, developing applications for it and actively helping us to improve it. For that, we are profoundly grateful. Many of our customers have now used three generations of our products and have experienced the advancement of the technology over the years while others have only recently discovered the capabilities microcalorimety can provide to their research. There are now over 7,900 peer reviewed publications that include data collected on MicroCal products. We are delighted to have so many members of the extended MicroCal family.
We are often asked if we are working on the next generation of ITC and DSC products; the answer to that question is always, definitely yes. We are always working to improve the sensitivity, reliability, and ease-of-use of our products. We have many exciting developments underway that we hope will expand and extend the usefulness of our technology for the determination and characterization of biomolecular interactions and the assessment of stability. Our best source of ideas for new technology innovation and products comes from understanding our customers’ problems. Solving the problems that are important to you is our best means to ensure our own future prosperity. So when you hear us asking you about “the problems in your lab that you would like help with,” please don’t be bashful about telling us how we can help you.