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2018
Activated Protein C blocks the inhibitory effect on neurite outgrowth by extracellular histones that mediates its inhibition through a retrograde YB-1 signal
July 9, 2018
Exosomes derived from high-glucose-stimulated Schwann cells promote development of diabetic peripheral neuropathy.
FASEB J. 2018 Jun 22:fj201800597R. doi: 10.1096/fj.201800597R. [Epub ahead of print]
Microfluidics of Small-Population Neurons Allows for a Precise Quantification of the Peripheral Axonal Growth State
Front Cell Neurosci. 2018; 12: 166. June 15, 2018
Advances in ex vivo models and lab-on-a-chip devices for neural tissue engineering.
Biomaterials. 2018 May 11. pii: S0142-9612(18)30347-8. doi: 10.1016/j.biomaterials.2018.05.012. [Epub ahead of print]
Neuronal subtype determines HSV-1 Latency-Associated-Transcript (LAT) promoter activity during latency.
J Virol. 2018 Apr 11. pii: JVI.00430-18. doi: 10.1128/JVI.00430-18. [Epub ahead of print]
Axonal Activation of the Unfolded Protein Response Promotes Axonal Regeneration Following Peripheral Nerve Injury.
Neuroscience. 2018 Apr 1;375:34-48. doi: 10.1016/j.neuroscience.2018.02.003. Epub 2018 Feb 10.
Exosomes taken up by neurons hijack the endosomal pathway to spread to interconnected neurons.
Acta Neuropathol Commun. 2018 Feb 15;6(1):10. doi: 10.1186/s40478-018-0514-4.
Neurturin is a PGC-1a1-controlled myokine that promotes motor neuron recruitment and neuromuscular junction formation.
Mol Metab. 2018 Jan;7:12-22. doi: 10.1016/j.molmet.2017.11.001. Epub 2017 Nov 7.
Importin α1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons.
PLoS Pathog. 2018 Jan 5;14(1):e1006823. doi: 10.1371/journal.ppat.1006823. eCollection 2018 Jan.
Visualization of local phosphatidylcholine synthesis within hippocampal neurons using a compartmentalized culture system and imaging mass spectrometry
Biochem Biophys Res Commun. 2018 Jan 1;495(1):1048-1054. doi: 10.1016/j.bbrc.2017.11.108. Epub 2017 Nov 21.
Intercellular transfer of pathogenic a-synuclein by extracellular vesicles is induced by the lipid peroxidation product 4-hydroxynonenal
Neurobiol Aging. 2018 Jan;61:52-65. doi: 10.1016/j.neurobiolaging.2017.09.016. Epub 2017 Sep 22.
2017
Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling.
Nat Commun. 2017 Sep 20;8(1):625.
Microfluidic Device for Studying Traumatic Brain Injury
Part of the Neuromethods book series (NM, volume 126) First Online: 12 May 2017
Mild and repetitive very mild axonal stretch injury triggers cystoskeletal mislocalization and growth cone collapse
PLoS One. 2017; 12(5): e0176997. Published online 2017 May 4.
Using high-throughput barcode sequencing to efficiently map connectomes
Nucleic Acids Res. 2017 Jul 7. 45(12): e115. Published online 2017 Apr 26
Messenger RNAs localized to distal projections of human stem cell derived neurons.
Sci Rep 7. 2017 Apr 4;7(1):611. Published online
NGF-dependent axon growth and regeneration are altered in sympathetic neurons of dystrophic mdx mice.
Mol Cell Neurosci. 2017 Feb 2;80:1-17 [Epub ahead of print]
T-type Ca2+ channels are required for enhanced sympathetic axon growth by TNFα reverse signaling Open Biology. Published 18 January 2017.DOI: 10.1098/rsob.160288
The release and trans-synaptic transmission of Tau via exosomes
Mol Neurodegener. 2017; 12: 5. Published online 2017 Jan 13.
MiR-29c/PRKCI Regulates Axonal Growth of Dorsal Root Ganglia Neurons Under Hyperglycemia.
Mol Neurobiol. 2017 Jan 9. [Epub ahead of print]
Co-culture Synaptogenic Assay: A New Look at Fluorescence Reporters and Technological Devices.
Methods Mol Biol. 2017;1538:13-27qua
2016
Acetylated tubulin is essential for touch sensation in mice
eLife. 2016; 5: e20813. Published online 2016 Dec 13
Mesenchymal Stromal Cells Promote Axonal Outgrowth Alone and Synergistically with Astrocytes via tPA
PLoS One. 2016; 11(12): e0168345. Published online 2016 Dec 13.
Compartmentalized Microfluidic Platforms: The Unrivaled Breakthrough of In Vitro Tools for Neurobiological Research.
J Neurosci. 2016 Nov 16;36(46):11573-11584.
Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3
Science. 2016 Sep 30; 353(6307): aah3374.
TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington’s disease
Proc Natl Acad Sci U S A. 2016 Sep 20; 113(38): E5655–E5664. Published online 2016 Sep 6.
Interneuronal Transfer and Distal Action of Tetanus Toxin and Botulinum Neurotoxins A and D in Central Neurons.
Cell Rep. 2016 Aug 16;16(7):1974-87. doi: 10.1016/j.celrep.2016.06.104. Epub 2016 Aug 4.
Probing extracellular Sonic hedgehog in neurons.
Biol Open. 2016 Aug 15;5(8):1086-92. doi: 10.1242/bio.019422.
Leucine Zipper-bearing Kinase promotes axon growth in mammalian central nervous system neurons
Sci Rep. 2016; 6: 31482. Published online 2016 Aug 11.
miR-145 Regulates Diabetes-Bone Marrow Stromal Cell-Induced Neurorestorative Effects in Diabetes Stroke Rats.
Stem Cells Transl Med. 2016 Jul 26. pii: sctm.2015-0349. [Epub ahead of print]
Semaphorin 3C Released from a Biocompatible Hydrogel Guides and Promotes Axonal Growth of Rodent and Human Dopaminergic Neurons.
Tissue Eng Part A. 2016 Jun;22(11-12):850-61. doi: 10.1089/ten.TEA.2016.0008.
A New Defective Helper RNA to Produce Recombinant Sindbis Virus that Infects Neurons but does not Propagate
Front Neuroanat. 2016; 10: 56. Published online 2016 May 24. doi: 10.3389/fnana.2016.00056
Monitoring mRNA Translation in Neuronal Processes Using Fluorescent Non-Canonical Amino Acid Tagging.
J Histochem Cytochem. 2016 May;64(5):323-33. doi: 10.1369/0022155416641604. Epub 2016 Mar 29.
MicroRNA 146a locally mediates distal axonal growth of dorsal root ganglia neurons under high glucose and sildenafil conditions.
Neuroscience. 2016 Aug 4;329:43-53. doi: 10.1016/j.neuroscience.2016.05.005. Epub 2016 May 7.
Retrograde fibroblast growth factor 22 (FGF22) signaling regulates insulin-like growth factor 2 (IGF2) expression for activity-dependent synapse stabilization in the mammalian brain.
Elife. 2016 Apr 15;5. pii: e12151. doi: 10.7554/eLife.12151.
Exosomes Derived from Mesenchymal Stromal Cells Promote Axonal Growth of Cortical Neurons.
Mol Neurobiol. 2016 Mar 19. [Epub ahead of print]
The RNA-binding protein SFPQ orchestrates an RNA regulon to promote axon viability.
Nat Neurosci. 2016 May;19(5):690-6. doi: 10.1038/nn.4280. Epub 2016 Mar 28.
Quantitative and semi-quantitative measurements of axonal degeneration in tissue and primary neuron cultures
J Neurosci Methods. 2016 Jun 15; 266: 32–41. Published online 2016 Mar 28.
Functional Impact of Corticotropin-Releasing Factor Exposure on Tau Phosphorylation and Axon Transport.
PLoS One. 2016 Jan 20;11(1):e0147250. doi: 10.1371/journal.pone.0147250. eCollection 2016.
Compartmentalized Platforms for Neuro-Pharmacological Research.
Curr Neuropharmacol. 2016;14(1):72-86.
D-4F Decreases White Matter Damage After Stroke in Mice
Stroke. 2016 Jan;47(1):214-20. doi: 10.1161/STROKEAHA.115.011046. Epub 2015 Nov 24.
2015
Dual Role of Herpes Simplex Virus 1 pUS9 in Virus Anterograde Axonal Transport and Final Assembly in Growth Cones in Distal Axons.
J Virol. 2015 Dec 23;90(5):2653-63. doi: 10.1128/JVI.03023-15.
The Basic Domain of Herpes Simplex Virus 1 pUS9 Recruits Kinesin-1 To Facilitate Egress from Neurons.
J Virol. 2015 Dec 9;90(4):2102-11. doi: 10.1128/JVI.03041-15.
Dendrosomatic Sonic Hedgehog Signaling in Hippocampal Neurons Regulates Axon Elongation
J Neurosci. 2015 Dec 9; 35(49): 16126–16141.
MicroRNAs in the axon locally mediate the effects of chondroitin sulfate proteoglycans and cGMP on axonal growth
Dev Neurobiol. 2015 Dec; 75(12): 1402–1419. Published online 2015 Jun 24.
Whole transcriptome profiling reveals the RNA content of motor axons
Nucleic Acids Res. 2016 Feb 29; 44(4): e33. Published online 2015 Oct 12.
Synaptic Contacts Enhance Cell-to-Cell Tau Pathology Propagation. Cell Rep. 2015 May 26;11(8):1176-83
Morphometric assessment of toxicant induced neuronal degeneration in full and restricted contact co-cultures of embryonic cortical rat neurons and astrocytes: using m-Dinitrobezene as a model neurotoxicant. Toxicol In Vitro. 2015 Apr;29(3):564-74.
Coupled local translation and degradation regulate growth cone collapse
Nat Commun. 2015; 6: 6888. Published online 2015 Apr 22.
Control of autophagosome axonal retrograde flux by presynaptic activity unveiled using botulinum neurotoxin type a J Neurosci. 2015 Apr 15;35(15):6179-94
Activation of 5-HT7 receptor stimulates neurite elongation through mTOR, Cdc42 and actin filaments dynamics. Front Behav Neurosci. 2015 Mar 11;9:62.
Identifying the primary site of pathogenesis in amyotrophic lateral sclerosis – vulnerability of lower motor neurons to proximal excitotoxicity
Dis Model Mech. 2015 Mar; 8(3): 215–224.
Recording large extracellular spikes in microchannels along many axonal sites from individual neurons. PLoS One. 2015 Mar 3;10(3):e0118514.
Increased migration of olfactory ensheathing cells secreting the Nogo receptor ectodomain over inhibitory substrates and lesioned spinal cord. Cell Mol Life Sci. 2015 Feb 24.
A ?-secretase inhibitor, but not a ?-secretase modulator, induced defects in BDNF axonal trafficking and signaling: evidence for a role for APP. PLoS One. 2015 Feb 24;10(2):e0118379.
2014
Herpes simplex virus gE/gI extracellular domains promote axonal transport and spread from neurons to epithelial cells. J Virol. 2014 Oct;88(19):11178-86.
PTEN inhibition enhances neurite outgrowth in human embryonic stem cell-derived neuronal progenitor cells. J Comp Neurol. 2014 Aug 15;522(12):2741-55.
A-synuclein immunotherapy blocks uptake and templated propagation of misfolded a-synuclein and neurodegeneration. Cell Rep. 2014 Jun 26;7(6):2054-65.
Regulation of axon growth by the JIP1-AKT axis. Dajas-Bailador F, Bantounas I, Jones EV, Whitmarsh AJ. J Cell Sci. 2014 Jan 1;127(Pt 1):230-9.
2013
Probing functional properties of nociceptive axons using a microfluidic culture system. PLoS One. 2013 Nov 20;8(11)
Microfluidic primary culture model of the lower motor neuron-neuromuscular junction circuit. J Neurosci Methods. 2013 Sep 15;218(2):164-9.
Dendritic GluN2A synthesis mediates activity-induced NMDA receptor insertion. J Neurosci. 2013 May 15;33(20):8898-908.
ProNGF promotes neurite growth from a subset of NGF-dependent neurons by a p75NTR-dependent mechanism. Development. 2013 May;140(10):2108-17.
The MicroRNA-17-92 cluster enhances axonal outgrowth in embryonic cortical neurons. J Neurosci. 2013 Apr 17;33(16):6885-94.
Axonal translation of β-catenin regulates synaptic vesicle dynamics. J Neurosci. 2013 Mar 27;33(13):5584-9.
Target-derived neurotrophins coordinate transcription and transport of bclw to prevent axonal degeneration. J Neurosci. 2013 Mar 20;33(12):5195-207.
Herpes simplex virus membrane proteins gE/gI and US9 act cooperatively to promote transport of capsids and glycoproteins from neuron cell bodies into initial axon segments. J Virol. 2013 Jan;87(1):403-14
Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons. J Biol Chem. 2013 Jan 18;288(3):1856-70.
2012
Neuron-to-neuron transmission of α-synuclein fibrils through axonal transport. Ann Neurol. 2012 Oct;72(4):517-24.
Axonal outgrowth and dendritic plasticity in the cortical peri-infarct area after experimental stroke. Stroke. 2012 Aug;43(8):2221-8.
A herpes simplex virus 1 (McKrae) mutant lacking the glycoprotein K gene is unable to infect via neuronal axons and egress from neuronal cell bodies. MBio. 2012 Jul 24;3(4):e00144-12.
Control of viral latency in neurons by axonal mTOR signaling and the 4E-BP translation repressor. Genes Dev. 2012 Jul 15;26(14):1527-32.
Assembly and maintenance of nodes of ranvier rely on distinct sources of proteins and targeting mechanisms. Neuron. 2012 Jan 12;73(1):92-107.
Chronic excitotoxin-induced axon degeneration in a compartmented neuronal culture model. ASN Neuro. 2012 Feb 23;4(1).
Chemical genetic-mediated spatial regulation of protein expression in neurons reveals an axonal function for wld(s). Chem Biol. 2012 Feb 24;19(2):179-87.
Microfluidics Platforms for Investigating Injury and Regeneration of CNS Axons. Ann Biomed Eng. 2012 Jun;40(6):1268-76.
2011
Microfluidic and Compartmentalized platforms for neurobiological research. Crit Rev Biomed Eng. 2011;39(3):185-200.
Neurotrophin-mediated dendrite-to-nucleus signaling revealed by microfluidic compartmentalization of dendrites. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11246-51.
Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson’s disease. Cell Death Differ. 2012 Mar;19(3):416-27.
The bovine herpesvirus type 1 envelope protein Us9 acidic domain is crucial for anterograde axonal transport. Vet Microbiol. 2011 Sep 28;152(3-4):270-9.
IL-1β inhibits axonal growth of developing sympathetic neurons. Mol Cell Neurosci. 2011 Oct;48(2):142-50.
Micro-scale and microfluidic devices for neurobiology. Curr Opin Neurobiol. 2010 Oct;20(5):640-7.
Examination of axonal injury and regeneration in micropatterned neuronal culture using pulsed laser microbeam dissection. Lab Chip. 2010 Aug 21;10(16):2083-92.
Anterograde transport of herpes simplex virus capsids in neurons by both Separate and Married mechanisms. J Virol. 2011 Jun;85(12):5919-28.
Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization. RNA. 2011 Jan;17(1):85-98.
Regulation of trafficking of activated TrkA is critical for NGF-mediated functions. Traffic. 2011 Apr;12(4):521-34.
2010
Microfluidic local perfusion chambers for the visualization and manipulation of synapses. Neuron. 2010 Apr 15;66(1):57-68.
2009
Shear stress effect on transfection of neurons cultured in microfluidic devices. J Nanosci Nanotechnol. 2009 Dec;9(12):7330-5.
Novel microfluidic platform for culturing neurons: culturing and biochemical analysis of neuronal components. Biotechnol J. 2009 Nov;4(11):1573-7.
Axonal elongation triggered by stimulus-induced local translation of a polarity complex protein. Nat Cell Biol. 2009 Aug;11(8):1024-30.
beta-Amyloid impairs axonal BDNF retrograde trafficking. Neurobiol Aging. 2011 May;32(5):821-33.
Axonal mRNA in uninjured and regenerating cortical mammalian axons. J Neurosci. 2009 Apr 15;29(15):4697-707.
Presynaptic regulation of astroglial excitatory neurotransmitter transporter GLT1. Neuron. 2009 Mar 26;61(6):880-94.
2008
A microfluidic chamber for analysis of neuron-to-cell spread and axonal transport of an alpha-herpesvirus. PLoS One. 2008 Jun 18;3(6):e2382.
2006
Microfluidic chambers for cell migration and neuroscience research. Methods Mol Biol. 2006;321:167-77.
Microfluidic culture platform for neuroscience research. Nat Protoc. 2006;1(4):2128-36.
2005
A microfluidic culture platform for CNS axonal injury, regeneration and transport. Nat Methods. 2005 Aug;2(8):599-605. |
