| 产品名称 | Biochips芯片 |
| 品牌 | cellix |
| 产品货号 | Biochips芯片 |
| 产品价格 | 现货询价 |
| 联系人 | 李先生 |
| 联系电话 | 18618101725 |
| 产品说明
Biochips
Cell Adhesion & Cell Culture under Flow, Transmigration, Droplet Generation and Microfluidics Studies
一、在剪切流下细胞-配体/细胞-蛋白粘附芯片
二、在剪切流下细胞培养 ＆细胞间粘附芯片
三、在剪切流下细胞-配体和细胞-细胞粘附芯片 五、VenaDelta Y2 模拟分支微血管网络，分支 Y 型接头在输入和输出端口
在剪切流下
DropChips are fabricated from plastic (acrylic) and have a footprint of 40mm x 50mm (W x L).
DropChips are available with channels pre-treated as hydrophobic or hydrophilic:
Hydrophobic to achieve water-in-oil droplets.
Hydrophilic to achieve oil-in-water droplets.
DropChips are available in packs of 2, 5 or 10.
Hydrophobic channels:
Water-in-oil droplet generation
Hydrophilic channels:
Oil-in-water droplet generation
As illustrated in the schematic below, each DropChip contains:
1 x Flow Splitter and
3 x Droplet Generator junctions:
2 x Flow-Focusing junctions, single-injection dispersed phase
1 x Flow Focusing junction with dual-injection dispersed phase
This gives the user flexibility for experiments in flow focusing with single and dual-injection of dispersed phase.
Examples are illustrated in the images below.
Droplet Frequency
The creation of uniform, mono-dispersed stable droplets is achieved with microfluidic syringe pumps such as Cellix's ExiGo pump or microfluidic pressure pumps such as Cellix's UniGo or 4U pumps. Cellix's team conducted 3D scattering measurements to confirm frequency of droplets which can be achieved at defined flow rates as illustrated in the images and frequency graph below. If you have a specific frequency you want to achieve, contact us for more help.
Droplet Frequency in DropChip with channel dimensions 70um x 70um
Droplet Size
There are a variety of different droplet sizes possible and one of the biggest influencing factors of droplet size is the geometry and size of the channel dimensions. Cellix's team conducted 3D scattering measurements to confirm size and volume of droplets which can be achieved with the two different types of droplet generator contained in the DropChip. Schematics for each of the droplet generators available on Cellix's Dropchip are illustrated below and the following table provides a summary of the droplet sizes (diameter and volume) which may be achieved depending on the DropChip dimensions.
Droplet Generator junction 1 & 3 (DG1 and DG3):
Flow Focusing, single injection of dispersed phase
Droplet Generator junction 2 (DG2):
Flow Focusing, dual injection of dispersed phase
Droplet Generation for a wide variety of applications:
Cell / Protein encapsulation and sorting on-chip, see example below.
DNA sequencing for target selection / enrichment.
Sample / reagent mixing and control of reactions on-chip
DNA amplification
Biomolecule synthesis
Diagnostic chips
Drug discovery
For more details on experimental set-ups, visit our Droplet Generation page.
Cell (or particle) double encapsulation:
The image below illustrates droplets containing cells, enclosed within a shell of oil. The following is an example of the experimental set-up to achieve double encapsulation.
Experimental Set-up
3 x ExiGo pumps
3 x Flow Sensors
1 x DropChip (50um x 50um) coated with DropCoat (reagent ensuring hydrophobicity)
1 x DropChip (80um x 80um) uncoated, hydrophilic walls
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