产品名称

CytoTrapNano循环肿瘤细胞分选系统 ,CytoTrapNanoTM CTC Systems,CytoTrapNanoTM Chip ,CytoTrapNano? CTC Assay,CytoTrapNanoTM PDMS Substrate Cover,CytoTrapNano? Manual Chip Holder

品牌

产品货号

CytoTrapNano循环肿瘤细胞分选系统 ,CytoTrapNanoTM CTC Systems,CytoTrapNanoTM Chip ,CytoTrapNano? CTC Assay,CytoTrapNanoTM PDMS Substrate Cover,CytoTrapNano? Manual Chip Holder

产品价格

现货询价

联系人

李先生

联系电话

18618101725

产品说明
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CytoTrapNano循环肿瘤细胞分选系统

CytoTrapNano? CTC Enumeration System
The CytoTrapNano? CTC Enumeration System is a semi-automatic system that can capture and quantify CTCs from a standard blood sample with a high level of sensvity and specificity.

The CytoTrapNano? system is comprised of the following three components:
1) the chip holder and fluidic handler to house the CytoTrapNano? Chip and overlaid PDMS chaotic mixer, allowing for highly efficient CTC capture from a pre-processed blood sample, 2) a fluorescence microscope for imaging CTCs immobilized on a CytoTrapNano? Chip, and 3) reagent kits. In general, it takes less then 3 h to run multiple CTC enumeration studies in parallel using an array of CytoTrapNano? Systems.

CytoLumina is developing a premarket notification based on the successful demonstration of substantial equivalence of the CytoTrapNano? to the CellSearch? Epithelial Cell Kit/Cell Spotter Analyzer (Veridex, Raritan, NJ) cleared under K073338, for the purpose of enumerating CTCs in patients with metastatic prostate cancer.

该系统为医疗保健和研究专业人员提供灵敏和特异的检测，用于检测和分析 CTC.

CytoTrapNano® 系统已用于同行评审研究，以从血液或其他液体样本中捕获稀有细胞，包括循环肿瘤细胞 (CTC) 和循环胎儿有核细胞 (CFNC)。

用生物素化抗体标记的细胞被专门捕获在 CytoTrapNano® 芯片上。

仅供科研使用 (RUO)。

关键技术特点：
专利技术平台——CytoTrapNano® 系统采用革命性的、专利的细胞亲和纳米结构基底分选平台、集成微流体系统和新型免疫化学程序。
高特异性和准确性 - CytoTrapNano® 系统捕获 CTC 的能力已得到证实，ICC 和高分辨率形态学进一步证实了这一点。
经验证的技术 - 在多个医疗机构进行科学验证，结果发表在具有高影响力的同行评审期刊上。

通过 CytoTrapNano® 设备捕获和识别 CTC 和其他稀有细胞

在 CytoTrapNano® 芯片上捕获和免疫荧光染色的细胞可以用荧光显微镜观察。* CytoTrapNano® 系统已用于临床研究以捕获来自前列腺癌、皮肤癌、胰腺癌、肝癌、肾癌和肺癌患者的 CTC。这些设备还被用于临床研究，以捕获和识别从孕妇抽取的血液中的稀有胎儿细胞。这些结果发表在高影响力期刊上。

*注意：由于芯片的不透明特性，显微镜的光源和镜头必须在芯片的同一侧。
对于 CTC 相关研究，可以使用 RUO 试剂盒。
对于涉及其他稀有细胞的研究，用户需要使用自己的捕获抗体和染色溶液。

CTC分选芯片-CytoTrapNano^TM 芯片(CytoTrapNano® Chip)

CytoTrapNano^TM 芯片是 Cytolumina Technologies 专有的微流体 CTC 捕获和筛选纳米技术产品。该芯片有一个带有 3 个并行通道的纳米蚀刻面。将芯片存放在 2-8°C.

细胞捕获和染色后，芯片可以很容易地附着在载玻片上，并用荧光显微镜检查。

CytoTrapNano^TM PDMS 底物盖，CytoTrapNano^TM PDMS Substrate Cover

CytoTrapNanoTM PDMS 底物盖可确保芯片在 CTC 富集过程中牢固地固定在芯片架中。盖子有一个包含入口和出口孔的纳米蚀刻面。在室温 (20-25oC) 下储存 CytoTrapNanoTM PDMS 底物盖

CytoTrapNano® 手动芯片架

CytoTrapNano® 手动芯片架是一种紧凑、简单的设备，可确保芯片和 PDMS 盖在 CTC 富集和固定过程中牢固固定以形成微流体通道。 CytoTrapNano® 芯片支架可与标准注射泵系统一起使用，以捕获 CytoTrapNano® 芯片上的细胞。

该平台已通过 Tygon 管 0.04" ID x 0.07" OD 和注射泵成功测试。

自动化解决方案

CytoTrapNanoTM 注射泵系统是一种易于使用的quan自动 CTC 富集和染色系统。它通过 TR（热释放）-CytoTrapNanoTM 系统实现 CTC 收集和保存，用于分子检测开发.

应用-关键研究：

Prostate Cancer

(1) Highly efficient capture of circulating tumor cells by using nanostructured silicon substrates with integrated chaotic micromixers. S Wang, K Liu, J Liu, ZTF Yu, X Xu, L Zhao, T Lee, EK Lee, J Reiss, ...Angewandte Chemie 123 (13), 3140-3144

(2) NanoVelcro Chip for CTC enumeration in prostate cancer patients. YT Lu, L Zhao, Q Shen, MA Garcia, D Wu, S Hou, M Song, X Xu, ...Methods 64 (2), 144-152

(3) High‐purity prostate circulating tumor cell isolation by a polymer nanofiber‐embedded microchip for whole exome sequencing. L Zhao, YT Lu, F Li, K Wu, S Hou, J Yu, Q Shen, D Wu, M Song, ... Advanced materials 25 (21), 2897-2902

(4) Subclassification of prostate cancer circulating tumor cells by nuclear size reveals very small nuclear circulating tumor cells in patients with visceral metastases. JF Chen, H Ho, J Lichterman, YT Lu, Y Zhang, MA Garcia, SF Chen, ...Cancer 121 (18), 3240-3251

Melanoma

(5) Polymer nanofiber‐embedded microchips for detection, isolation, and molecular analysis of single circulating melanoma cells. S Hou, L Zhao, Q Shen, J Yu, C Ng, X Kong, D Wu, M Song, X Shi, X Xu, ...Angewandte Chemie International Edon 52 (12), 3379-3383

Pancreatic Cancer

(6) Circulating tumour cells as a biomarker for diagnosis and staging in pancreatic cancer. JS Ankeny, CM Court, S Hou, Q Li, M Song, D Wu, JF Chen, T Lee, M Lin,...Brsh journal of cancer 114 (12), 1367

(7) Circulating Tumor Cells Predict Occult Metastatic Disease and Prognosis in Pancreatic Cancer. JS Ankeny, S Sho, P Winograd, S Hou, M Song, ZA Wainberg, MD Girgis, ...Annals of Surgical Oncology, 1-9

Hepatocellular Carcinoma

(8) Evaluation of hepatocellular carcinoma circulating tumor cells expressing programmed death-ligand 1. P Winograd, S Hou, S Sadeghi, RS Finn, B DiPardo, Q Li, FM Kaldas, ...HPB 20, S2-S3

(9) A Novel Multimarker Assay for the Phenotypic Profiling of Circulating Tumor Cells in Hepatocellular Carcinoma. CM Court, S Hou, P Winograd, NH Segel, QW Li, Y Zhu, S Sadeghi, ...Liver Transplantation

Non-Small Cell Lung Cancer

(10) Programming thermoresponsiveness of NanoVelcro substrates enables effective purification of circulating tumor cells in lung cancer patients. Z Ke, M Lin, JF Chen, J Choi, Y Zhang, A Fong, AJ Liang, SF Chen, Q Li, ...ACS nano 9 (1), 62-70

Kidney Cancer

(11) Combined cell surface carbonic anhydrase 9 and CD147 antigens enable high-efficiency capture of circulating tumor cells in clear cell renal cell carcinoma patients. S Liu, Z Tian, L Zhang, S Hou, S Hu, J Wu, Y Jing, H Sun, F Yu, L Zhao, ...Oncotarget 7 (37), 59877

Fetal cells

(12) Imprinted NanoVelcro Microchips for Isolation and Characterization of Circulating Fetal Trophoblasts: Toward Noninvasive Prenatal Diagnostics (vol 11, pg 8167, 2017). S Hou, JF Chen, M Song, Y Zhu, YJ Jan, SH Chen, TH Weng, DA Ling, ...ACS NANO 11 (12), 12863-12863

Review Articles

(13) Nanostructure embedded microchips for detection, isolation, and characterization of circulating tumor cells M Lin, JF Chen, YT Lu, Y Zhang, J Song, S Hou, Z Ke, HR Tseng Accounts of chemical research 47 (10), 2941-2950

(14) NanoVelcro rare-cell assays for detection and characterization of circulating tumor cells. YJ Jan, JF Chen, Y Zhu, YT Lu, SH Chen, H Chung, M Smalley, ...Advanced drug delivery reviews 125, 78-93

(15) Clinical applications of NanoVelcro rare-cell assays for detection and characterization of circulating tumor cells JF Chen, Y Zhu, YT Lu, E Hodara, S Hou, VG Agopian, JS Tomlinson, ...Theranostics 6 (9), 1425

(16) Noninvasive Prenatal Diagnostics: Recent Developments Using Circulating Fetal Nucleated Cells PJ Chen, PC Teng, Y Zhu, YJ Jan, M Smalley, Y Afshar, LC Chen, ...Current Obstetrics and Gynecology Reports, 1-8

文献：

Publications

Y.J. Jan, J. Yoon, J.-F. Chen, P.-C. Teng, N. Yao, S. Cheng, A. Lozano, C.-Y. Chu, H. Chung, Y.-T. Lu, P.-J. Chen, J.J. Wang, Y.-T. Lee, Y. Zhu, B.S. Knudsen, F.Y. Feng, I.P. Garraway, A.C. Gao, L.W.K. Chung, M.R. Freeman, S. You, H.-R. Tseng, E.M. Posadas (2019) A Circulating Tumor Cell-RNA Assay for Assessment of Androgen Receptor Signaling Inhibitor Sensvity in Metastatic Castration-Resistant Prostate Cancer. Theranostics; 9: In press. PMCID: PMC6568173
J. Dong, R.Y. Zhang, N. Sun, M. Smalley, Z. Wu, A. Zhou, S.J. Chou, Y.J. Jan, P. Yang, L. Bao, D. Qi, X. Tang, P. Tseng, Y. Hua, D. Xu, R. Kao, M. Meng, X. Zheng, Y. Liu, T. Vagner, X. Chai, D. Zhou, M. Li, S.H. Chiou, G. Zheng, D. Di Vizio, V.G. Agopian, E.M. Posadas, S.J. Jonas, S.P. Ju, P.S. Weiss, M. Zhao, H.-R. Tseng, and Y. Zhu (2019) Bio-Inspired NanoVilli Chips for Enhanced Capture of Tumor-Derived Extracellular Vesicles: Toward Non-Invasive Detection of Gene Alterations in Non-Small Cell Lung Cancer. ACS Appl. Mater. Interfaces; 11: In press. PMCID: PMC6545291
M. Hou, Y. Zheng, Z. Ding, S. He, M. Xu, X. Chen, H. Zheng, C. Sun, W. Jiang, H. Wang, H. Shen, Y. Zhang, J. Liu, S. Sun, N. Jiang, Y. Cui, Y. Sun, Y. Chen, J. Cao, C. Wang, M. Li, Y. Zhang, J. Wang, M. Lin, Z. Ke (2019) The Role of a Semi-Automated NanoVelcro System in Capturing Circulating Tumor Cells and Evaluating Their Prognostic Value for Gestational Choriocarcinoma. Biomater. Sci.; 2019, 7, 1200-1210. In Press. PMID: 30656300
W. He, M. Hou, H. Zhang, C. Zeng, S. He, X. Chen, M. Xu, C. Sun, W. Jiang, H. Wang, H. Shen, Y. Zhang, J. Liu, S. Sun, N. Jiang, Y. Cui, Y. Sun, Y. Chen, J. Cao, C. Wang, M. Li, Y. Xhang, L. Wang, J. Wang, M. Lin, Z. Ke (2018) Clinical significanve of circulating tumor cells in predicting disease progression and chemotherapy resistance in patients with gestational choriocarcinoma. International Journal of Cancer; 144(6), 1241-1431: In Press. PMCID: PMC658745
M. Reis-Sobreiro, J.-F. Chen, T. Novitskaya, S. You, S. Morley, K. Steadman, N.K. Gill, A. Eskaros, M. Rotinen, C.-Y. Chu, L.W.K. Chung, H. Tanaka, W. Yang, B.S. Knudsen, H.-R. Tseng, A.C. Rowat, E.M. Posadas, A. Zijlstra, D. Di Vizio, M.R. Freeman (2018) Emerin Deregulation Links Nuclear Shape Instability to Metastatic Potential, Cancer Research, Cancer Res; 78(21); 6086–97.
A.F. Salem, S. Wang, S. Billet, J.-F. Chen, P. Udompholkul, L. Gambini, C. Baggio, H.-R. Tseng, E.M. Posadas, N.A. Bhowmick, M. Pellecchia (2018) Reduction of Circulating Cancer Cells and Metastases in Breast-Cancer Models by a Potent EphA2-Agonistic Peptide–Drug Conjugate, J. Med. Chem., 61 (5), 2052–2061. PMCID: PMC5907794
C.M. Court, S. Hou, P. Winograd, N.H. Segel, Q. Wilda Li, Y. Zhu, S. Sadeghi, R.S. Finn, E. Ganapathy, M. Song, S.W. French, B. Naini, S. Sho, F.M. Kaldas, R.W. Busuttil, J.S. Tomlinson, H.-R. Tseng, V.G. Agopian (2018) A Novel Multimarker Assay for the Phenotypic Profiling of Circulating Tumor Cells in Hepatocellular Carcinoma, Liver Transplantation, 24(7), 946-960. PMCID: PMC6097911
Y.J. Jan, J.-F. Chen, Y. Zhu, Y.-T. Lu, S.H. Chen, H. Chung, M. Smalley, Y.-W. Huang, Ji. Dong, L.-C. Chen, H.-H. Yu, J.S. Tomlinson, Hou, V. G. Agopian, E. M. Posadas, H.-R. Tseng (2018) NanoVelcro Rare-Cell Assays for Detection and Characterization of Circulating Tumor Cells, Adv. Drug Delivery Rev. 125: 78-93. PMCID: PMC5993593
C.M. Court, J.S. Ankeny, S. Sho, P. Winograd, S. Hou, M. Song, Z.A. Wainberg, M.D. Girgis, T.G. Graeber, V.G. Agopian, H.-R. Tseng, J.S. Tomlinson (2018) Circulating Tumor Cells Predict Occult Metastatic Disease and Prognosis in Pancreatic Cancer, Ann. Surg. Oncol. 25(X): In press. PMCID: PMC5896564
M.-Y. Shen, J.-F. Chen, C.-H. Luo, S. Lee, C.-H. Li, Y.-L. Yang, Y.-H. Tsai, B.-C. Ho, L.-R. Bao, T.-J. Lee, Y.J. Jan, Y. Zhu, S. Cheng, F.Y. Feng, P. Chen, S. Hou., V. Agopian., Y.-S. Hsiao, H.-R. Tseng, E.M. Posadas, H. Yu (2018) Glycan Stimulation Enables Purification of Prostate Cancer Circulating Tumor Cells on PEDOT NanoVelcro Chips for RNA Biomarker Detection, Adv. HealthCare Mater. 6(X): In press. PMCID: PMC5803304
S. Sho, P. Winograd, S. Lee, S. Hou, T. G. Graeber, H.-R. Tseng, J.S. Tomlinson (2017) Precision Oncology Using a Limited Number of Cells: Optimization of Whole Genome Amplification Products for Sequencing Applications, BMC Cancer, 17, 457-470. PMCID: PMC5493892
S. Hou, M. Lin, J.-F. Chen, M. Song, Y. Zhu, Y.J. Jan, S. H. Chen, T.-H. Weng, D.-A. Ling, S.-F. Chen, T. Ro, A.-J. Liang, T. Lee, H. Jin, M. Li, L. Liu, Y. S. Hsiao, P. Chen, H. Yu, M.-S. Tsai, M. D. Pisarska, A. Chen, L.-C. Chen, H.-R. Tseng (2017) Imprinted NanoVelcro Microchips for Isolation and Characterization of Circulating Fetal Trophoblasts: Toward Noninvasive Prenatal Diagnostics, ACS Nano, 11(8): 8167-8177. PMCID: PMC5614709
R.L. Grossman, B. Abel, S. Angiuoli, J.C. Barrett, D. Bassett, K. Bramlett, G.M. Blumenthal, A. Carlsson, R. Cortese, J. DiGiovanna, B. Davis-Dusenbery, R. Dittamore, D.A. Eberhard, P. Febbo, M. Fitzsimons, Z. Flamig, J. Godsey, J. Goswami, A. Gruen, F.O. Guzman, J. Han , D. Hayes, J. Hicks, D. Holloway, D. Hovelson, J. Johnson, H. Juhl, R. Kalamegham, R. Kamal, Q. Kang, G.J. Kelloff, M. Klozenbuecher, A. Kolatkar, P. Kuhn, K. Langone, R. Leary, P. Loverso, H. Manmathan, A.M. Martin, J. Martini, D. Miller, M. Mitchell, T. Morgan, R. Mulpuri, T. Nguyen, G. Otto, A. Pathak, E. Peters, R. Philip, E. Posadas, D. Reese, M.G. Reese, D. Robinson, A.D. Rossi, H. Sakul, J. Schageman, S. Singh, H.I. Scher, K. Schmitt, A. Silvestro, J. Simmons, T. Simmons, J. Sislow, A. Talasaz, P. Tang, M. Tewari, S. Tomlins, H. Toukhy, H.-R. Tseng, M. Tuck, A. Tzou, J. Vinson, Y. Wang, W. Wells, A. Welsh, J. Wilbanks, J. Wolf, L. Young, J.S. Lee, L.C. Leiman (2017) Clin Pharmacol Ther. 101 (5): 589-592. PMCID: PMC5525192
J.F. Chen, Y.T. Lu, S. Cheng , H.-R. Tseng, R.A. Figlin, E.M. Posadas (2017) Circulating Tumor Cells in Prostate Cancer: Beyond Enumeration, Clin. Adv. Hematol. Oncol. 15(1): 63-73.
S. Cheng, J.-F. Chen, Y.-T. Lu, L. W.K. Chung, H.-R. Tseng, E.M. Posadas (2016) Applications of Circulating Tumor Cells for Prostate Cancer, Asian Journal of Urology, 3(4): 254-259. PMCID: PMC5730870
R. Wang, C.-Y. Chu, S. Mrdenovic, A.A. Annamalai, A.E. Hendifar, N. N. Nissen, J.S. Tomlinson, M. Lewis, N. Palanisamy, H.-R. Tseng, E.M. Posadas, S.J. Pandol, H.E. Zhau, L.W.K. Chung (2016) Cultured Circulating Tumor Cells and Their Derived Xenografts for Personalized Oncology, Asian Journal of Urology, 3(4): 240-253. PMCID: PMC5730836
S. Liu, Z. Tian, L. Zhang, S. Hou, S. Hu, J. Wu, Y. Jing, H. Sun, F. Yu, L. Zhao, R. Wang, H.-R. Tseng, H. E. Zhau, L.W. Chung, K. Wu, H. Wang, J.B. Wu, Y. Nie, C. Shao (2016) Combined Cell Surface Carbonic Anhydrase 9 and CD147 Antigens Enable High-Efficiency Capture of Circulating Tumor Cells in Clear Cell Renal Cell Carcinoma Patients, Oncotarget, 7(37):59877-59891. PMCID: PMC5312355
C. M. Court, J. S. Ankeny, S. Sho, S. Hou, Q. Li, C. Hsieh, M. Song, X. Liao, M. M. Rochefort, Z. Wainberg, T. Graeber, H.-R. Tseng, J. S. Tomlinson (2016) Reality of Single Circulating Tumor Cell Sequencing for Molecular Diagnostics in Pancreatic Cancer, J. Mol. Diagn. In press. PMCID: PMC5397706
J.-F. Chen, Y. Zhu, Y.-T. Lu, E. Hodara, S. Hou, V. G. Agopian, J. S. Tomlinson, E. M. Posadas, H.-R. Tseng (2016) Clinical Applications of NanoVelcro Rare-Cell Assays for Detection and Characterization of Circulating Tumor Cells, Theranostics, 6(9): 1425-1439. PMCID: PMC4924510
J. Ankeny, C. Court, S. Hou, Q. Li, M. Song, D. Wu, J.-F. Chen, T. Lee, M. Lin, S. Sho, M. Rochefort, M. Girgis, J. Yao, Z. Wainberg, V. Muthusamy, R. Watson, T. Donahue, O. Hines, H. Reber, T. Graeber, H.-R. Tseng, and J. Tomlinson (2016) Circulating Tumor Cells as a Biomarker for Diagnosis and Staging in Pancreatic Cancer, Br. J. Cancer, 114, 1367–1375. PMCID: PMC4984454
W. He, D. Xu, Z. Wang, X. Xiang, B. Tang, S. Li, M. Hou, Y. Zhang, J.-F Chen, M. Lin, L. Wang, S. Hou, H.-R. Tseng, M. Kuang, Z.-F. Ke (2016) Detecting ALK-Rearrangement of CTC Enriched by NanoVelcro Chip in Advanced NSCLC Patients, Oncotarget, 7: in press. PMCID: in process
L. Zhao, C. Tang, L. Xu, Z. Zhang, X. Li, H. Hu, S. Cheng, W. Zhou, M. Huang, A. Fong, B. Liu, H.-R. Tseng, H. Gao, Y. Liu, X. Fang (2016) Enhanced and Differential Capture of Circulating Tumor Cells from Lung Cancer Patients by Microfluidic Assays Using Aptamer Cocktail, Small, 12(8):1072-81. PMCID: PMC4893320
R. Jiang, Y.-T. Lu, H. Ho, B. Li, J.-F. Chen, M. Lin, F. Li, K. Wu, H. Wu, J. Lichterman, Hao. Wan, C.-L. Lu, W. OuYang, M. Ni, L. Wang, G. Li, T. Lee, X. Zhang, J. Yang, M. Rettig, L.W.K. Chung, H. Yang, K.-C. Li, Y. Hou, H.-R. Tseng, S. Hou, X. Xu, J. Wang, E.M. Posadas (2015) A Comparison of Isolated Circulating Tumor Cells and Tissue Biopsies Using Whole-Genome Sequencing in Prostate Cancer, Oncotarget, 6(42): 44781-44793. PMCID: PMC4792591
C.M. Court, J.S. Ankeny, S. Hou, H.-R. Tseng, J.S Tomlinson (2015) Improving Pancreatic Cancer Diagnosis Using Circulating Tumor Cells, Prospects for Staging and Single-Cell Analysis, Expert Review of Molecular Diagnostics, 15(11): 1491-1504. PMCID: PMC4893319
J.-F. Chen, H. Ho, J. Lichterman, Y.-T. Lu, Y. Zhang, M. A. Garcia, S.-F. Chen, A.-J. Liang, S. Hou, R. S. Ahmed, D. J. Luthringer, J. Huang, K.-C. Li, L. W.K. Chung, Z. Ke, H.-R. Tseng , E. M. Posadas (2015) Subclassification of Prostate Cancer Circulating Tumor Cells by Nuclear Size Reveals Very Small Nuclear Circulating Tumor Cells in Patients with Visceral Metastases, Cancer, 121: 3240–3251. PMCID: PMC4560974
Z. Ke, M. Lin, J.-F. Chen, J.-S. Choi, Y. Zhang, A. Fong, A.-J. Liang, S.-F. Chen, Q. Li, M. A. Garcia, T. Lee, M. Song, H.-A. Lin, H. Zhao, S.-C. Luo, S. Hou, H. Yu, H.-R. Tseng (2015) Programming Thermoresponsiveness of NanoVelcro Substrates Enables Effective Purification of Circulating Tumor Cells in Lung Cancer Patients, ACS Nano. 9: 62-70. PMCID: PMC4310634
M. Lin, J.-F. Chen, Y.-T. Lu, Y. Zhang, J. Song, S. Hou, Z. Ke, H.-R. Tseng (2014) Nanostructures-Embedded Microchips for Detection, Isolation, and Characterization of Circulating Tumor Cells, Acc. Chem. Res. 47: 2941-2950. PMCID: PMC4204926
Y.-S. Hsiao, S.-C. Luo, S. Hou, B. Zhu, J. Sekine, C.-W. Kuo, D.-Y. Chueh, H. Yu, H.-R. Tseng, and P. Chen (2014) 3D Bioelectronic Interface: Capturing Circulating Tumor Cells onto Conducting Polymer-Based Micro/Nanorod Arrays with Chemical and Topographical Control, Small, 10: 3012–3017. PMCID: PMC4125486
Y.-T. Lu, L. Zhao, Q. Shen, M. A. Garcia, D. Wu, S. Hou, M. Song, X. Xu, W.-H. OuYang, Z. Luo, T. Lee, .X. Xuan, J. Huang, L. W. K. Chung, M. Rettig, H.-R. Tseng, C. Shao, E. M. Posadas (2013) NanoVelcro Chip for CTC Enumeration in Prostate Cancer Patients, Methods, 64:144-152. PMCID: PMC3834112
L. Zhao, Y.-T. Lu, F. Li, K. Wu, S. Hou, J. Yu, Q. Shen, D. Wu, M. Song, W.-H. OuYang, Z. Luo, T. Lee, C. Shao, X. Xu, M. A. Garcia, L. W. K. Chung, M. Rettig, H.-R. Tseng, E. M. Posadas (2013) High-Purity Prostate Circulating Tumor Cell Isolation by a Polymer Nanofiber-Embedded Microchip for Whole Exome Sequencing, Adv. Mater. 25: 2897-2902. PMCID: PMC3875622(Internal Cover Highlight)
Q. Shen, L. Xu, L. Zhao, D. Wu, Y. Fan, Y. Zhou, W.-H. OuYang, X. Xu, Z. Zhang, T. Lee, B. Xiong, S. Hou, H.-R. Tseng, X. Fang (2013) Specific Capture and Release of Circulating Tumor Cells Using Aptamer Modified Nanosubstrates, Adv. Mater. 25: 2368–2373. PMCID: PMC3786685
S. Hou, Q. Shen, L. Zhao, J. Yu, C. Ng, X. Kong, D. Wu, M. Song, X. Shi, X. Xu, W.-H. OuYang, R. He, X.-Z. Zhao, B. Xiong, T. Lee, C. Brunicardi, M. A. Garcia, A. Ribas, R. S. Lo, H.-R. Tseng (2013) Polymer Nanofiber-Embedded Microchips for Detection, Isolation, and Molecular Analysis of Single Circulating Melanoma Cells. Angew. Chem. Int. Ed. 52: 3379–3383. PMCID: PMC3807678 (Internal Cover Highlight)
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